Cargando…
Improving yield of a recombinant biologic in a Brassica hairy root manufacturing process
Hairy root systems have proven to be a viable alternative for recombinant protein production. For recalcitrant proteins, maximizing the productivity of hairy root cultures is essential. The aim of this study was to optimize a Brassica rapa rapa hairy root process for secretion of alpha‐ l‐iduronidas...
Autores principales: | Gutierrez‐Valdes, Noemi, Häkkinen, Suvi T., Lemasson, Camille, de Groot, Jonas, Ele‐Ekouna, Jean‐Pierre, Guillet, Marina, Cardon, Florian, Ritala, Anneli |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543041/ https://www.ncbi.nlm.nih.gov/pubmed/35822204 http://dx.doi.org/10.1002/bit.28178 |
Ejemplares similares
-
Hairy Root Cultures—A Versatile Tool With Multiple Applications
por: Gutierrez-Valdes, Noemi, et al.
Publicado: (2020) -
Brassica rapa hairy root based expression system leads to the production of highly homogenous and reproducible profiles of recombinant human alpha‐L‐iduronidase
por: Cardon, Florian, et al.
Publicado: (2018) -
Tobacco BY-2 Media Component Optimization for a Cost-Efficient Recombinant Protein Production
por: Häkkinen, Suvi T., et al.
Publicado: (2018) -
Single Cell Protein—State-of-the-Art, Industrial Landscape and Patents 2001–2016
por: Ritala, Anneli, et al.
Publicado: (2017) -
Exploring the Metabolic Stability of Engineered Hairy Roots after 16 Years Maintenance
por: Häkkinen, Suvi T., et al.
Publicado: (2016)