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Recombinant l‐Amino Acid Oxidase with Broad Substrate Spectrum for Co‐substrate Recycling in (S)‐Selective Transaminase‐Catalyzed Kinetic Resolutions

Chiral and enantiopure amines can be produced by enantioselective transaminases via kinetic resolution of amine racemates. This transamination reaction requires stoichiometric amounts of co‐substrate. A dual‐enzyme recycling system overcomes this limitation: l‐amino acid oxidases (LAAO) recycle the...

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Detalles Bibliográficos
Autores principales:	Heinks, Tobias, Paulus, Jannik, Koopmeiners, Simon, Beuel, Tobias, Sewald, Norbert, Höhne, Matthias, Bornscheuer, Uwe T., Fischer von Mollard, Gabriele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543090/ https://www.ncbi.nlm.nih.gov/pubmed/35713203 http://dx.doi.org/10.1002/cbic.202200329

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