Anesthetic considerations in Dravet syndrome

We describe a two‐year‐old boy with Dravet syndrome, a severe genetic epilepsy, who developed a generalized tonic–clonic seizure immediately following an intravenous bolus of lidocaine given for propofol pain amelioration during induction of anesthesia for emergency gastroscopy. Although lidocaine h...

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Detalles Bibliográficos
Autores principales: Macdonald‐Laurs, Emma, Corlette, Sebastian, Davidson, Andrew, Howell, Katherine B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543092/
https://www.ncbi.nlm.nih.gov/pubmed/35816396
http://dx.doi.org/10.1111/pan.14525
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author Macdonald‐Laurs, Emma
Corlette, Sebastian
Davidson, Andrew
Howell, Katherine B.
author_facet Macdonald‐Laurs, Emma
Corlette, Sebastian
Davidson, Andrew
Howell, Katherine B.
author_sort Macdonald‐Laurs, Emma
collection PubMed
description We describe a two‐year‐old boy with Dravet syndrome, a severe genetic epilepsy, who developed a generalized tonic–clonic seizure immediately following an intravenous bolus of lidocaine given for propofol pain amelioration during induction of anesthesia for emergency gastroscopy. Although lidocaine has not specifically been reported as potentiating seizures in Dravet syndrome, it is well‐established that sodium channel blockers can worsen seizures in this population.
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spelling pubmed-95430922022-10-14 Anesthetic considerations in Dravet syndrome Macdonald‐Laurs, Emma Corlette, Sebastian Davidson, Andrew Howell, Katherine B. Paediatr Anaesth Case Reports We describe a two‐year‐old boy with Dravet syndrome, a severe genetic epilepsy, who developed a generalized tonic–clonic seizure immediately following an intravenous bolus of lidocaine given for propofol pain amelioration during induction of anesthesia for emergency gastroscopy. Although lidocaine has not specifically been reported as potentiating seizures in Dravet syndrome, it is well‐established that sodium channel blockers can worsen seizures in this population. John Wiley and Sons Inc. 2022-07-20 2022-10 /pmc/articles/PMC9543092/ /pubmed/35816396 http://dx.doi.org/10.1111/pan.14525 Text en © 2022 The Authors. Pediatric Anesthesia published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Macdonald‐Laurs, Emma
Corlette, Sebastian
Davidson, Andrew
Howell, Katherine B.
Anesthetic considerations in Dravet syndrome
title Anesthetic considerations in Dravet syndrome
title_full Anesthetic considerations in Dravet syndrome
title_fullStr Anesthetic considerations in Dravet syndrome
title_full_unstemmed Anesthetic considerations in Dravet syndrome
title_short Anesthetic considerations in Dravet syndrome
title_sort anesthetic considerations in dravet syndrome
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543092/
https://www.ncbi.nlm.nih.gov/pubmed/35816396
http://dx.doi.org/10.1111/pan.14525
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