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Anesthetic considerations in Dravet syndrome
We describe a two‐year‐old boy with Dravet syndrome, a severe genetic epilepsy, who developed a generalized tonic–clonic seizure immediately following an intravenous bolus of lidocaine given for propofol pain amelioration during induction of anesthesia for emergency gastroscopy. Although lidocaine h...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543092/ https://www.ncbi.nlm.nih.gov/pubmed/35816396 http://dx.doi.org/10.1111/pan.14525 |
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author | Macdonald‐Laurs, Emma Corlette, Sebastian Davidson, Andrew Howell, Katherine B. |
author_facet | Macdonald‐Laurs, Emma Corlette, Sebastian Davidson, Andrew Howell, Katherine B. |
author_sort | Macdonald‐Laurs, Emma |
collection | PubMed |
description | We describe a two‐year‐old boy with Dravet syndrome, a severe genetic epilepsy, who developed a generalized tonic–clonic seizure immediately following an intravenous bolus of lidocaine given for propofol pain amelioration during induction of anesthesia for emergency gastroscopy. Although lidocaine has not specifically been reported as potentiating seizures in Dravet syndrome, it is well‐established that sodium channel blockers can worsen seizures in this population. |
format | Online Article Text |
id | pubmed-9543092 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-95430922022-10-14 Anesthetic considerations in Dravet syndrome Macdonald‐Laurs, Emma Corlette, Sebastian Davidson, Andrew Howell, Katherine B. Paediatr Anaesth Case Reports We describe a two‐year‐old boy with Dravet syndrome, a severe genetic epilepsy, who developed a generalized tonic–clonic seizure immediately following an intravenous bolus of lidocaine given for propofol pain amelioration during induction of anesthesia for emergency gastroscopy. Although lidocaine has not specifically been reported as potentiating seizures in Dravet syndrome, it is well‐established that sodium channel blockers can worsen seizures in this population. John Wiley and Sons Inc. 2022-07-20 2022-10 /pmc/articles/PMC9543092/ /pubmed/35816396 http://dx.doi.org/10.1111/pan.14525 Text en © 2022 The Authors. Pediatric Anesthesia published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Case Reports Macdonald‐Laurs, Emma Corlette, Sebastian Davidson, Andrew Howell, Katherine B. Anesthetic considerations in Dravet syndrome |
title | Anesthetic considerations in Dravet syndrome |
title_full | Anesthetic considerations in Dravet syndrome |
title_fullStr | Anesthetic considerations in Dravet syndrome |
title_full_unstemmed | Anesthetic considerations in Dravet syndrome |
title_short | Anesthetic considerations in Dravet syndrome |
title_sort | anesthetic considerations in dravet syndrome |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543092/ https://www.ncbi.nlm.nih.gov/pubmed/35816396 http://dx.doi.org/10.1111/pan.14525 |
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