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Improved Antibody‐Specific Epitope Prediction Using AlphaFold and AbAdapt

Antibodies recognize their cognate antigens with high affinity and specificity, but the prediction of binding sites on the antigen (epitope) corresponding to a specific antibody remains a challenging problem. To address this problem, we developed AbAdapt, a pipeline that integrates antibody and anti...

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Detalles Bibliográficos
Autores principales: Xu, Zichang, Davila, Ana, Wilamowski, Jan, Teraguchi, Shunsuke, Standley, Daron M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543094/
https://www.ncbi.nlm.nih.gov/pubmed/35893479
http://dx.doi.org/10.1002/cbic.202200303