Cargando…
Improved Antibody‐Specific Epitope Prediction Using AlphaFold and AbAdapt
Antibodies recognize their cognate antigens with high affinity and specificity, but the prediction of binding sites on the antigen (epitope) corresponding to a specific antibody remains a challenging problem. To address this problem, we developed AbAdapt, a pipeline that integrates antibody and anti...
Autores principales: | Xu, Zichang, Davila, Ana, Wilamowski, Jan, Teraguchi, Shunsuke, Standley, Daron M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543094/ https://www.ncbi.nlm.nih.gov/pubmed/35893479 http://dx.doi.org/10.1002/cbic.202200303 |
Ejemplares similares
-
AbAdapt: an adaptive approach to predicting antibody–antigen complex structures from sequence
por: Davila, Ana, et al.
Publicado: (2022) -
AlphaFold and the future of structural biology
por: Read, Randy J., et al.
Publicado: (2023) -
Deciphering cross-species reactivity of LAMP-1 antibodies using deep mutational epitope mapping and AlphaFold
por: Pruvost, Tiphanie, et al.
Publicado: (2023) -
AlphaFold, Artificial
Intelligence (AI), and Allostery
por: Nussinov, Ruth, et al.
Publicado: (2022) -
Applying and improving AlphaFold at CASP14
por: Jumper, John, et al.
Publicado: (2021)