High frequency of CD8 escape mutations in elite controllers as new obstacle for HIV cure

Accumulation of mutations in epitopes of cytolytic-T-lymphocytes immune response (CTL) in HIV-reservoir seems to be one of the reasons for shock-and-kill strategy failure. Ten non-controller patients on successful cART (TX) and seven elite controllers (EC) were included. HIV-Gag gene from purified r...

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Detalles Bibliográficos
Autores principales: Navarrete-Muñoz, María A., Ramos, Ricardo, Holguín, África, Cabello, Alfonso, Górgolas, Miguel, Benito, José M., Rallón, Norma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543107/
https://www.ncbi.nlm.nih.gov/pubmed/36190143
http://dx.doi.org/10.1080/21505594.2022.2129353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543107/
https://www.ncbi.nlm.nih.gov/pubmed/36190143
http://dx.doi.org/10.1080/21505594.2022.2129353

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