Bone marrow CD3 (+) CD56 (+) regulatory T lymphocytes (T(R3) (−56) cells) are inversely associated with activation and expansion of bone marrow cytotoxic T cells in IPSS‐R very‐low/low risk MDS patients

BACKGROUND: Emergence of dysplastic haematopoietic precursor/s, cytopenia and variable leukaemia risk characterise myelodysplastic syndromes (MDS). Impaired immune‐regulation, preferentially affecting cytotoxic T cells (CTL), has been largely observed in MDS. Recently, we described the T(R3−56) T ce...

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Detalles Bibliográficos
Autores principales: Leone, Stefania, Rubino, Valentina, Palatucci, Anna Teresa, Giovazzino, Angela, Carriero, Flavia, Cerciello, Giuseppe, Pane, Fabrizio, Ruggiero, Giuseppina, Terrazzano, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543123/
https://www.ncbi.nlm.nih.gov/pubmed/35775392
http://dx.doi.org/10.1111/ejh.13822

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