Tuning Electrostatic and Hydrophobic Surfaces of Aromatic Rings to Enhance Membrane Association and Cell Uptake of Peptides

Aromatic groups are key mediators of protein–membrane association at cell surfaces, contributing to hydrophobic effects and π‐membrane interactions. Here we show electrostatic and hydrophobic influences of aromatic ring substituents on membrane affinity and cell uptake of helical, cyclic and cell pe...

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Detalles Bibliográficos
Autores principales: de Araujo, Aline D., Hoang, Huy N., Lim, Junxian, Mak, Jeffrey Y. W., Fairlie, David P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543247/
https://www.ncbi.nlm.nih.gov/pubmed/35523729
http://dx.doi.org/10.1002/anie.202203995

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