Cargando…

Secoisolariciresinol diglucoside induces pyroptosis by activating caspase‐1 to cleave GSDMD in colorectal cancer cells

Secoisolariciresinol diglucoside (SDG) is the main component of lignans with various biological activities, including anticancer activity. However, whether SDG has obvious anticancer effects on colorectal cancer (CRC) is unclear. Pyroptosis, a form of programmed cell death, has received increasing a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Tuo, Wang, Zhen, Zhong, Junbo, Zhang, Lijun, Zhang, Haopeng, Zhang, Dayong, Xu, Xiaofeng, Zhong, Xianfei, Wang, Jing, Li, Hai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543314/ https://www.ncbi.nlm.nih.gov/pubmed/35472101 http://dx.doi.org/10.1002/ddr.21939

Ejemplares similares

Potential protective properties of flax lignan secoisolariciresinol diglucoside
por: Imran, Muhammad, et al.
Publicado: (2015)

Secoisolariciresinol Diglucoside of Flaxseed and Its Metabolites: Biosynthesis and Potential for Nutraceuticals
por: Kezimana, Parfait, et al.
Publicado: (2018)

Secoisolariciresinol Diglucoside Improves Ovarian Reserve in Aging Mouse by Inhibiting Oxidative Stress
por: He, XueLai, et al.
Publicado: (2022)

Identification and functional characterization of a flax UDP-glycosyltransferase glucosylating secoisolariciresinol (SECO) into secoisolariciresinol monoglucoside (SMG) and diglucoside (SDG)
por: Ghose, Kaushik, et al.
Publicado: (2014)

Secoisolariciresinol diglucoside regulates estrogen receptor expression to ameliorate OVX-induced osteoporosis
por: Chen, Guofang, et al.
Publicado: (2023)

Secoisolariciresinol Diglucoside Abrogates Oxidative Stress-Induced Damage in Cardiac Iron Overload Condition
por: Puukila, Stephanie, et al.
Publicado: (2015)

UGT74S1 is the key player in controlling secoisolariciresinol diglucoside (SDG) formation in flax
por: Fofana, Bourlaye, et al.
Publicado: (2017)

Flaxseed lignans enriched in secoisolariciresinol diglucoside prevent acute asbestos-induced peritoneal inflammation in mice
por: Pietrofesa, Ralph A., et al.
Publicado: (2016)

Secoisolariciresinol diglucoside is a blood-brain barrier protective and anti-inflammatory agent: implications for neuroinflammation
por: Rom, Slava, et al.
Publicado: (2018)

Secoisolariciresinol diglucoside and anethole ameliorate lipid abnormalities, oxidative injury, hypercholesterolemia, heart, and liver conditions
por: Noreen, Sana, et al.
Publicado: (2023)

The Synthetic Lignan Secoisolariciresinol Diglucoside Prevents Asbestos-Induced NLRP3 Inflammasome Activation in Murine Macrophages
por: Pietrofesa, Ralph A., et al.
Publicado: (2017)

Secoisolariciresinol Diglucoside Delays the Progression of Aging-Related Diseases and Extends the Lifespan of Caenorhabditis elegans via DAF-16 and HSF-1
por: Lu, Min, et al.
Publicado: (2020)

Simvastatin induces pyroptosis via ROS/caspase-1/GSDMD pathway in colon cancer
por: Xie, Wei, et al.
Publicado: (2023)

Synthetic Secoisolariciresinol Diglucoside (LGM2605) Protects Human Lung in an Ex Vivo Model of Proton Radiation Damage
por: Velalopoulou, Anastasia, et al.
Publicado: (2017)

Synthetic Secoisolariciresinol Diglucoside Attenuates Established Pain, Oxidative Stress and Neuroinflammation in a Rodent Model of Painful Radiculopathy
por: Kartha, Sonia, et al.
Publicado: (2020)

Caspase-1 cleaves Bid to release mitochondrial SMAC and drive secondary necrosis in the absence of GSDMD
por: Heilig, Rosalie, et al.
Publicado: (2020)

Tetracaine hydrochloride induces macrophage pyroptosis through caspase‑1/11‑GSDMD signaling pathways
por: Zhang, Ran, et al.
Publicado: (2023)

The Flaxseed-Derived Lignan Phenolic Secoisolariciresinol Diglucoside (SDG) Protects Non-Malignant Lung Cells from Radiation Damage
por: Velalopoulou, Anastasia, et al.
Publicado: (2015)

Synthetic Lignan Secoisolariciresinol Diglucoside (LGM2605) Reduces Asbestos-Induced Cytotoxicity in an Nrf2-Dependent and -Independent Manner
por: Pietrofesa, Ralph A., et al.
Publicado: (2018)

Synthetic Secoisolariciresinol Diglucoside (LGM2605) Prevents Asbestos-Induced Inflammation and Genotoxic Cell Damage in Human Mesothelial Cells
por: Pietrofesa, Ralph A., et al.
Publicado: (2022)

Talaromyces marneffei activates the AIM2-caspase-1/-4-GSDMD axis to induce pyroptosis in hepatocytes
por: Wang, Gang, et al.
Publicado: (2022)

GSDMD-Mediated Cardiomyocyte Pyroptosis Promotes Myocardial I/R Injury
por: Shi, Huairui, et al.
Publicado: (2021)

The flaxseed lignan secoisolariciresinol diglucoside decreases local inflammation, suppresses NFκB signaling, and inhibits mammary tumor growth
por: Bowers, Laura W., et al.
Publicado: (2018)

Induced Mutagenesis in UGT74S1 Gene Leads to Stable New Flax Lines with Altered Secoisolariciresinol Diglucoside (SDG) Profiles
por: Fofana, Bourlaye, et al.
Publicado: (2017)

Copper Oxide Nanoparticle-Induced Acute Inflammatory Response and Injury in Murine Lung Is Ameliorated by Synthetic Secoisolariciresinol Diglucoside (LGM2605)
por: Pietrofesa, Ralph A., et al.
Publicado: (2021)

Triclabendazole Induces Pyroptosis by Activating Caspase-3 to Cleave GSDME in Breast Cancer Cells
por: Yan, Liang, et al.
Publicado: (2021)

Ophiopogonin B alleviates cisplatin resistance of lung cancer cells by inducing Caspase-1/GSDMD dependent pyroptosis
por: Cheng, Ziyu, et al.
Publicado: (2022)

Laser Microdissection and Spatiotemporal Pinoresinol-Lariciresinol Reductase Gene Expression Assign the Cell Layer-Specific Accumulation of Secoisolariciresinol Diglucoside in Flaxseed Coats
por: Fang, Jingjing, et al.
Publicado: (2016)

Data on cecal and fecal microbiota and predicted metagenomes profiles of female mice receiving whole flaxseed or its oil and secoisolariciresinol diglucoside components
por: Taibi, Amel, et al.
Publicado: (2021)

GSDMD contributes to myocardial reperfusion injury by regulating pyroptosis
por: Ye, Xiaomiao, et al.
Publicado: (2022)

Mycobacterium tuberculosis PE_PGRS19 Induces Pyroptosis through a Non-Classical Caspase-11/GSDMD Pathway in Macrophages
por: Qian, Jianing, et al.
Publicado: (2022)

Ionic Liquid-Based Ultrasonic-Assisted Extraction of Secoisolariciresinol Diglucoside from Flaxseed (Linum usitatissimum L.) with Further Purification by an Aqueous Two-Phase System
por: Tan, Zhi-Jian, et al.
Publicado: (2015)

Mitochondrial ROS promote macrophage pyroptosis by inducing GSDMD oxidation
por: Wang, Yufang, et al.
Publicado: (2019)

Secoisolariciresinol Diglucoside Exerts Anti-Inflammatory and Antiapoptotic Effects through Inhibiting the Akt/IκB/NF-κB Pathway on Human Umbilical Vein Endothelial Cells
por: Zhang, Shaoyang, et al.
Publicado: (2020)

Asbestos Induces Oxidative Stress and Activation of Nrf2 Signaling in Murine Macrophages: Chemopreventive Role of the Synthetic Lignan Secoisolariciresinol Diglucoside (LGM2605)
por: Pietrofesa, Ralph A., et al.
Publicado: (2016)

Cookies enriched with anethole and secoisolariciresinol diglucoside from flaxseed and fennel seeds improve hypercholesterolemia, lipid profile, and liver functions: A pilot study
por: Noreen, Sana, et al.
Publicado: (2023)

Didymin Suppresses Microglia Pyroptosis and Neuroinflammation Through the Asc/Caspase-1/GSDMD Pathway Following Experimental Intracerebral Hemorrhage
por: Gu, Lingui, et al.
Publicado: (2022)

Cold Stress Induced Liver Injury of Mice through Activated NLRP3/Caspase-1/GSDMD Pyroptosis Signaling Pathway
por: Liu, Yuanyuan, et al.
Publicado: (2022)

β-sitosterol alleviates dextran sulfate sodium-induced experimental colitis via inhibition of NLRP3/Caspase-1/GSDMD-mediated pyroptosis
por: Zhang, Di, et al.
Publicado: (2023)

The Inflammasome Drives GSDMD-Independent Secondary Pyroptosis and IL-1 Release in the Absence of Caspase-1 Protease Activity
por: Schneider, Katharina S., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_6ga2tiovk03q437ele9i0lafnp