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Prior term delivery increases risk of subsequent recurrent preterm birth: An unexpected finding
BACKGROUND: Women with a prior pregnancy at term are generally considered to be at reduced risk for subsequent spontaneous preterm birth (sPTB), whereas a previous sPTB is a major predictor for a future sPTB. AIMS: The objective of this study was to investigate the risk of recurrent sPTB in women wi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543374/ https://www.ncbi.nlm.nih.gov/pubmed/35220589 http://dx.doi.org/10.1111/ajo.13504 |
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author | Suff, Natalie Xu, Vicky X. Dalla Valle, Giorgia Carter, Jenny Brennecke, Shaun Shennan, Andrew |
author_facet | Suff, Natalie Xu, Vicky X. Dalla Valle, Giorgia Carter, Jenny Brennecke, Shaun Shennan, Andrew |
author_sort | Suff, Natalie |
collection | PubMed |
description | BACKGROUND: Women with a prior pregnancy at term are generally considered to be at reduced risk for subsequent spontaneous preterm birth (sPTB), whereas a previous sPTB is a major predictor for a future sPTB. AIMS: The objective of this study was to investigate the risk of recurrent sPTB in women with a prior term birth and a subsequent sPTB. MATERIALS AND METHODS: This is a retrospective cohort study conducted at St Thomas’ Hospital in London, UK. There were 430 women included: 230 with a term birth (caesarean section or vaginal delivery) preceding a sPTB (term + sPTB group) and 200 with a prior sPTB only (sPTB only group). The primary outcome was sPTB, <37 weeks gestation. RESULTS: Of the term + sPTB group, 38.7% (89/230) had a recurrent sPTB compared to 20% (40/200) in the sPTB only group (P < 0.0001), with a relative risk (RR) of 1.9. Of women who had a term caesarean section and a subsequent PTB, 50% (30/60) had a further sPTB (RR 2.5 compared to the sPTB only group), while 34.7% (59/170) of women who had a term vaginal birth and subsequent sPTB, had a further sPTB (RR 1.7 compared to the sPTB only group). CONCLUSION: In women who have had a previous sPTB, the risk of a recurrence is much higher than in women with a prior term birth. The aetiology of PTB may be different in this subgroup of women and needs to be further elucidated to determine how best to identify and treat them. |
format | Online Article Text |
id | pubmed-9543374 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-95433742022-10-14 Prior term delivery increases risk of subsequent recurrent preterm birth: An unexpected finding Suff, Natalie Xu, Vicky X. Dalla Valle, Giorgia Carter, Jenny Brennecke, Shaun Shennan, Andrew Aust N Z J Obstet Gynaecol Original Articles BACKGROUND: Women with a prior pregnancy at term are generally considered to be at reduced risk for subsequent spontaneous preterm birth (sPTB), whereas a previous sPTB is a major predictor for a future sPTB. AIMS: The objective of this study was to investigate the risk of recurrent sPTB in women with a prior term birth and a subsequent sPTB. MATERIALS AND METHODS: This is a retrospective cohort study conducted at St Thomas’ Hospital in London, UK. There were 430 women included: 230 with a term birth (caesarean section or vaginal delivery) preceding a sPTB (term + sPTB group) and 200 with a prior sPTB only (sPTB only group). The primary outcome was sPTB, <37 weeks gestation. RESULTS: Of the term + sPTB group, 38.7% (89/230) had a recurrent sPTB compared to 20% (40/200) in the sPTB only group (P < 0.0001), with a relative risk (RR) of 1.9. Of women who had a term caesarean section and a subsequent PTB, 50% (30/60) had a further sPTB (RR 2.5 compared to the sPTB only group), while 34.7% (59/170) of women who had a term vaginal birth and subsequent sPTB, had a further sPTB (RR 1.7 compared to the sPTB only group). CONCLUSION: In women who have had a previous sPTB, the risk of a recurrence is much higher than in women with a prior term birth. The aetiology of PTB may be different in this subgroup of women and needs to be further elucidated to determine how best to identify and treat them. John Wiley and Sons Inc. 2022-02-27 2022-08 /pmc/articles/PMC9543374/ /pubmed/35220589 http://dx.doi.org/10.1111/ajo.13504 Text en © 2022 The Authors. Australian and New Zealand Journal of Obstetrics and Gynaecology published by John Wiley & Sons Australia, Ltd on behalf of Royal Australian and New Zealand College of Obstetricians and Gynaecologists https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Articles Suff, Natalie Xu, Vicky X. Dalla Valle, Giorgia Carter, Jenny Brennecke, Shaun Shennan, Andrew Prior term delivery increases risk of subsequent recurrent preterm birth: An unexpected finding |
title | Prior term delivery increases risk of subsequent recurrent preterm birth: An unexpected finding |
title_full | Prior term delivery increases risk of subsequent recurrent preterm birth: An unexpected finding |
title_fullStr | Prior term delivery increases risk of subsequent recurrent preterm birth: An unexpected finding |
title_full_unstemmed | Prior term delivery increases risk of subsequent recurrent preterm birth: An unexpected finding |
title_short | Prior term delivery increases risk of subsequent recurrent preterm birth: An unexpected finding |
title_sort | prior term delivery increases risk of subsequent recurrent preterm birth: an unexpected finding |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543374/ https://www.ncbi.nlm.nih.gov/pubmed/35220589 http://dx.doi.org/10.1111/ajo.13504 |
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