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Sensitization of colonic nociceptors by TNFα is dependent on TNFR1 expression and p38 MAPK activity
ABSTRACT: Visceral pain is a leading cause of morbidity in gastrointestinal diseases, which is exacerbated by the gut‐related side‐effects of many analgesics. New treatments are needed and further understanding of the mediators and mechanisms underpinning visceral nociception in disease states is re...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543404/ https://www.ncbi.nlm.nih.gov/pubmed/35775903 http://dx.doi.org/10.1113/JP283170 |