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In Silico Modeling for Ex Vivo Placental Transfer of Morphine

Morphine may be administered in pregnant women as an analgesic agent. The transplacental pharmacokinetics (PK) of morphine varies during pregnancy because of physiological and metabolic changes. In this work, we use a multi‐compartment model to simulate ex vivo human placental transfer studies of mo...

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Detalles Bibliográficos
Autores principales:	Ho, Harvey, Zhang, Shengjie, Kurosawa, Ken, Chiba, Koji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Supplement Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543479/ https://www.ncbi.nlm.nih.gov/pubmed/36106779 http://dx.doi.org/10.1002/jcph.2105

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