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Homocysteine facilitates endoplasmic reticulum stress and apoptosis of hepatocytes by suppressing ERO1α expression via cooperation between DNMT1 and G9a
Endoplasmic reticulum (ER) stress and apoptosis play a critical role in liver injury. Endoplasmic reticulum oxidoreductase 1α (ERO1α) is an oxidase that exists in the luminal side of the ER membrane, participating in protein folding and secretion and inhibiting apoptosis, but the underlying mechanis...
Autores principales: | Shen, Jiangyong, Jiao, Yun, Ding, Ning, Xie, Lin, Ma, Shengchao, Zhang, Hui, Yang, Anning, Zhang, Huiping, Jiang, Yideng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543485/ https://www.ncbi.nlm.nih.gov/pubmed/35347798 http://dx.doi.org/10.1002/cbin.11805 |
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