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Homocysteine facilitates endoplasmic reticulum stress and apoptosis of hepatocytes by suppressing ERO1α expression via cooperation between DNMT1 and G9a

Endoplasmic reticulum (ER) stress and apoptosis play a critical role in liver injury. Endoplasmic reticulum oxidoreductase 1α (ERO1α) is an oxidase that exists in the luminal side of the ER membrane, participating in protein folding and secretion and inhibiting apoptosis, but the underlying mechanis...

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Detalles Bibliográficos
Autores principales: Shen, Jiangyong, Jiao, Yun, Ding, Ning, Xie, Lin, Ma, Shengchao, Zhang, Hui, Yang, Anning, Zhang, Huiping, Jiang, Yideng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543485/
https://www.ncbi.nlm.nih.gov/pubmed/35347798
http://dx.doi.org/10.1002/cbin.11805

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