Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases

OBJECTIVE: Copy number variation of the C4 complement components, C4A and C4B, has been associated with systemic inflammatory autoimmune diseases. This study was undertaken to investigate whether C4 copy number variation is connected to the autoimmune repertoire in systemic lupus erythematosus (SLE)...

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Autores principales: Lundtoft, Christian, Pucholt, Pascal, Martin, Myriam, Bianchi, Matteo, Lundström, Emeli, Eloranta, Maija‐Leena, Sandling, Johanna K., Sjöwall, Christopher, Jönsen, Andreas, Gunnarsson, Iva, Rantapää‐Dahlqvist, Solbritt, Bengtsson, Anders A., Leonard, Dag, Baecklund, Eva, Jonsson, Roland, Hammenfors, Daniel, Forsblad‐d'Elia, Helena, Eriksson, Per, Mandl, Thomas, Magnusson Bucher, Sara, Norheim, Katrine B., Auglænd Johnsen, Svein Joar, Omdal, Roald, Kvarnström, Marika, Wahren‐Herlenius, Marie, Notarnicola, Antonella, Andersson, Helena, Molberg, Øyvind, Diederichsen, Louise Pyndt, Almlöf, Jonas, Syvänen, Ann‐Christine, Kozyrev, Sergey V., Lindblad‐Toh, Kerstin, Nilsson, Bo, Blom, Anna M., Lundberg, Ingrid E., Nordmark, Gunnel, Diaz‐Gallo, Lina Marcela, Svenungsson, Elisabet, Rönnblom, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2022
Materias:
Autoimmune Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543510/
https://www.ncbi.nlm.nih.gov/pubmed/35315244
http://dx.doi.org/10.1002/art.42122

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