Cargando…
Tau and neurofilament light‐chain as fluid biomarkers in spinocerebellar ataxia type 3
BACKGROUND AND PURPOSE: Clinical trials in spinocerebellar ataxia type 3 (SCA3) will require biomarkers for use as outcome measures. METHODS: To evaluate total tau (t‐tau), glial fibrillary acidic protein (GFAP), ubiquitin carboxy‐terminal hydrolase L1 (UCHL1) and neurofilament light‐chain (NfL) as...
Autores principales: | Garcia‐Moreno, Hector, Prudencio, Mercedes, Thomas‐Black, Gilbert, Solanky, Nita, Jansen‐West, Karen R., Hanna AL‐Shaikh, Rana, Heslegrave, Amanda, Zetterberg, Henrik, Santana, Magda M., Pereira de Almeida, Luis, Vasconcelos‐Ferreira, Ana, Januário, Cristina, Infante, Jon, Faber, Jennifer, Klockgether, Thomas, Reetz, Kathrin, Raposo, Mafalda, Ferreira, Ana F., Lima, Manuela, Schöls, Ludger, Synofzik, Matthis, Hübener‐Schmid, Jeannette, Puschmann, Andreas, Gorcenco, Sorina, Wszolek, Zbigniew K., Petrucelli, Leonard, Giunti, Paola |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543545/ https://www.ncbi.nlm.nih.gov/pubmed/35478426 http://dx.doi.org/10.1111/ene.15373 |
Ejemplares similares
-
A next generation sequencing‐based analysis of a large cohort of ataxic patients refines the clinical spectrum associated with spinocerebellar ataxia 21
por: Riso, Vittorio, et al.
Publicado: (2021) -
Neurofilaments in spinocerebellar ataxia type 3: blood biomarkers at the preataxic and ataxic stage in humans and mice
por: Wilke, Carlo, et al.
Publicado: (2020) -
Infrequent SCN9A mutations in congenital insensitivity to pain and erythromelalgia
por: Klein, Christopher J, et al.
Publicado: (2013) -
Autosomal-recessive cerebellar ataxia caused by a novel ADCK3 mutation that elongates the protein: clinical, genetic and biochemical characterisation
por: Liu, Yo-Tsen, et al.
Publicado: (2014) -
Profilin1 E117G is a moderate risk factor for amyotrophic lateral sclerosis
por: Fratta, Pietro, et al.
Publicado: (2014)