Cargando…

Elastic stent recoil in coronary total occlusions: Comparison of durable‐polymer zotarolimus eluting stent and ultrathin strut bioabsorbable‐polymer sirolimus eluting stent

OBJECTIVES: To compare stent recoil (SR) of the thin‐strut durable‐polymer Zotarolimus‐eluting stent (dp‐ZES) and the ultrathin‐strut bioabsorbable‐polymer Sirolimus‐eluting stent (bp‐SES) in chronic total occlusions (CTOs) and to investigate the predictors of high SR in CTOs. BACKGROUND: Newer ultr...

Descripción completa

Detalles Bibliográficos
Autores principales: Improta, Riccardo, Scarparo, Paola, Wilschut, Jeroen, Wolff, Quinten, Daemen, Joost, Den Dekker, Wijnand K, Zijlstra, Felix, Van Mieghem, Nicolas M, Diletti, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543547/
https://www.ncbi.nlm.nih.gov/pubmed/33961730
http://dx.doi.org/10.1002/ccd.29739
_version_ 1784804398509064192
author Improta, Riccardo
Scarparo, Paola
Wilschut, Jeroen
Wolff, Quinten
Daemen, Joost
Den Dekker, Wijnand K
Zijlstra, Felix
Van Mieghem, Nicolas M
Diletti, Roberto
author_facet Improta, Riccardo
Scarparo, Paola
Wilschut, Jeroen
Wolff, Quinten
Daemen, Joost
Den Dekker, Wijnand K
Zijlstra, Felix
Van Mieghem, Nicolas M
Diletti, Roberto
author_sort Improta, Riccardo
collection PubMed
description OBJECTIVES: To compare stent recoil (SR) of the thin‐strut durable‐polymer Zotarolimus‐eluting stent (dp‐ZES) and the ultrathin‐strut bioabsorbable‐polymer Sirolimus‐eluting stent (bp‐SES) in chronic total occlusions (CTOs) and to investigate the predictors of high SR in CTOs. BACKGROUND: Newer ultrathin drug eluting stent might be associated with lower radial force and higher elastic recoil due to the thinner strut design, possibly impacting on the rate of in‐stent restenosis and thrombosis. METHODS: Between January 2017 and November 2019, consecutive patients with CTOs undergoing percutaneous coronary intervention were evaluated. Only patients treated with dp‐ZES or bp‐SES were included and stratified accordingly. Quantitative coronary angiography analysis was used to assess absolute SR, relative SR, absolute focal SR, relative focal SR, high absolute, and high relative focal SR. RESULTS: A total of 128 lesions (67 treated with dp‐ZES and 61 with bp‐SES) in 123 patients were analyzed. Between bp‐SES and dp‐ZES no differences were found in absolute SR (p = .188), relative SR (p = .138), absolute focal SR (p = .069), and relative focal SR (p = .064). High absolute and high relative focal SR occurred more frequently in bp‐SES than in dp‐ZES (p = .004 and p = .015). Bp‐SES was a predictor of high absolute focal SR (Odds ratio [OR] 3.29, 95% confidence interval [CI] 1.50–7.22, p = .003]. High‐pressure postdilation and bp‐SES were predictors of high relative focal SR (OR 2.22, 95% CI 1.01–4.86, p = .047; OR 2.74, 95% CI 1.24–6.02, p = .012, respectively). CONCLUSIONS: Both stents showed an overall low SR. However, ultra‐thin strut bp‐SES was a predictor of high absolute and high relative focal SR.
format Online
Article
Text
id pubmed-9543547
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher John Wiley & Sons, Inc.
record_format MEDLINE/PubMed
spelling pubmed-95435472022-10-14 Elastic stent recoil in coronary total occlusions: Comparison of durable‐polymer zotarolimus eluting stent and ultrathin strut bioabsorbable‐polymer sirolimus eluting stent Improta, Riccardo Scarparo, Paola Wilschut, Jeroen Wolff, Quinten Daemen, Joost Den Dekker, Wijnand K Zijlstra, Felix Van Mieghem, Nicolas M Diletti, Roberto Catheter Cardiovasc Interv Coronary Artery Disease OBJECTIVES: To compare stent recoil (SR) of the thin‐strut durable‐polymer Zotarolimus‐eluting stent (dp‐ZES) and the ultrathin‐strut bioabsorbable‐polymer Sirolimus‐eluting stent (bp‐SES) in chronic total occlusions (CTOs) and to investigate the predictors of high SR in CTOs. BACKGROUND: Newer ultrathin drug eluting stent might be associated with lower radial force and higher elastic recoil due to the thinner strut design, possibly impacting on the rate of in‐stent restenosis and thrombosis. METHODS: Between January 2017 and November 2019, consecutive patients with CTOs undergoing percutaneous coronary intervention were evaluated. Only patients treated with dp‐ZES or bp‐SES were included and stratified accordingly. Quantitative coronary angiography analysis was used to assess absolute SR, relative SR, absolute focal SR, relative focal SR, high absolute, and high relative focal SR. RESULTS: A total of 128 lesions (67 treated with dp‐ZES and 61 with bp‐SES) in 123 patients were analyzed. Between bp‐SES and dp‐ZES no differences were found in absolute SR (p = .188), relative SR (p = .138), absolute focal SR (p = .069), and relative focal SR (p = .064). High absolute and high relative focal SR occurred more frequently in bp‐SES than in dp‐ZES (p = .004 and p = .015). Bp‐SES was a predictor of high absolute focal SR (Odds ratio [OR] 3.29, 95% confidence interval [CI] 1.50–7.22, p = .003]. High‐pressure postdilation and bp‐SES were predictors of high relative focal SR (OR 2.22, 95% CI 1.01–4.86, p = .047; OR 2.74, 95% CI 1.24–6.02, p = .012, respectively). CONCLUSIONS: Both stents showed an overall low SR. However, ultra‐thin strut bp‐SES was a predictor of high absolute and high relative focal SR. John Wiley & Sons, Inc. 2021-05-07 2022-01-01 /pmc/articles/PMC9543547/ /pubmed/33961730 http://dx.doi.org/10.1002/ccd.29739 Text en © 2021 The Authors. Catheterization and Cardiovascular Interventions published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Coronary Artery Disease
Improta, Riccardo
Scarparo, Paola
Wilschut, Jeroen
Wolff, Quinten
Daemen, Joost
Den Dekker, Wijnand K
Zijlstra, Felix
Van Mieghem, Nicolas M
Diletti, Roberto
Elastic stent recoil in coronary total occlusions: Comparison of durable‐polymer zotarolimus eluting stent and ultrathin strut bioabsorbable‐polymer sirolimus eluting stent
title Elastic stent recoil in coronary total occlusions: Comparison of durable‐polymer zotarolimus eluting stent and ultrathin strut bioabsorbable‐polymer sirolimus eluting stent
title_full Elastic stent recoil in coronary total occlusions: Comparison of durable‐polymer zotarolimus eluting stent and ultrathin strut bioabsorbable‐polymer sirolimus eluting stent
title_fullStr Elastic stent recoil in coronary total occlusions: Comparison of durable‐polymer zotarolimus eluting stent and ultrathin strut bioabsorbable‐polymer sirolimus eluting stent
title_full_unstemmed Elastic stent recoil in coronary total occlusions: Comparison of durable‐polymer zotarolimus eluting stent and ultrathin strut bioabsorbable‐polymer sirolimus eluting stent
title_short Elastic stent recoil in coronary total occlusions: Comparison of durable‐polymer zotarolimus eluting stent and ultrathin strut bioabsorbable‐polymer sirolimus eluting stent
title_sort elastic stent recoil in coronary total occlusions: comparison of durable‐polymer zotarolimus eluting stent and ultrathin strut bioabsorbable‐polymer sirolimus eluting stent
topic Coronary Artery Disease
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543547/
https://www.ncbi.nlm.nih.gov/pubmed/33961730
http://dx.doi.org/10.1002/ccd.29739
work_keys_str_mv AT improtariccardo elasticstentrecoilincoronarytotalocclusionscomparisonofdurablepolymerzotarolimuselutingstentandultrathinstrutbioabsorbablepolymersirolimuselutingstent
AT scarparopaola elasticstentrecoilincoronarytotalocclusionscomparisonofdurablepolymerzotarolimuselutingstentandultrathinstrutbioabsorbablepolymersirolimuselutingstent
AT wilschutjeroen elasticstentrecoilincoronarytotalocclusionscomparisonofdurablepolymerzotarolimuselutingstentandultrathinstrutbioabsorbablepolymersirolimuselutingstent
AT wolffquinten elasticstentrecoilincoronarytotalocclusionscomparisonofdurablepolymerzotarolimuselutingstentandultrathinstrutbioabsorbablepolymersirolimuselutingstent
AT daemenjoost elasticstentrecoilincoronarytotalocclusionscomparisonofdurablepolymerzotarolimuselutingstentandultrathinstrutbioabsorbablepolymersirolimuselutingstent
AT dendekkerwijnandk elasticstentrecoilincoronarytotalocclusionscomparisonofdurablepolymerzotarolimuselutingstentandultrathinstrutbioabsorbablepolymersirolimuselutingstent
AT zijlstrafelix elasticstentrecoilincoronarytotalocclusionscomparisonofdurablepolymerzotarolimuselutingstentandultrathinstrutbioabsorbablepolymersirolimuselutingstent
AT vanmieghemnicolasm elasticstentrecoilincoronarytotalocclusionscomparisonofdurablepolymerzotarolimuselutingstentandultrathinstrutbioabsorbablepolymersirolimuselutingstent
AT dilettiroberto elasticstentrecoilincoronarytotalocclusionscomparisonofdurablepolymerzotarolimuselutingstentandultrathinstrutbioabsorbablepolymersirolimuselutingstent