Profiling of warfarin pharmacokinetics‐associated genetic variants: Black Africans portray unique genetic markers important for an African specific warfarin pharmacogenetics‐dosing algorithm

BACKGROUND: Warfarin dose variability observed in patients is attributed to variation in genes involved in the warfarin metabolic pathway. Genetic variation in CYP2C9 and VKORC1 has been the traditional focus in evaluating warfarin dose variability, with little focus on other genes. OBJECTIVE: We se...

Descripción completa

Detalles Bibliográficos
Autores principales: Ndadza, Arinao, Muyambo, Sarudzai, Mntla, Pindile, Wonkam, Ambroise, Chimusa, Emile, Kengne, Andre P., Ntsekhe, Mpiko, Dandara, Collet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
THROMBOSIS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543705/
https://www.ncbi.nlm.nih.gov/pubmed/34382722
http://dx.doi.org/10.1111/jth.15494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543705/
https://www.ncbi.nlm.nih.gov/pubmed/34382722
http://dx.doi.org/10.1111/jth.15494

Ejemplares similares