Toxic and nutritional factors trigger Leber hereditary optic neuropathy due to a mitochondrial tRNA mutation

Leber hereditary optic neuropathy is a mitochondrial disease mainly due to pathologic mutations in mitochondrial genes related to the respiratory complex I of the oxidative phosphorylation system. Genetic, physiological, and environmental factors modulate the penetrance of these mutations. We report...

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Detalles Bibliográficos
Autores principales: Vela‐Sebastián, Ana, López‐Gallardo, Ester, Emperador, Sonia, Hernández‐Ainsa, Carmen, Pacheu‐Grau, David, Blanco, Ignacio, Ros, Andrea, Pascual‐Benito, Ester, Rabaneda‐Lombarte, Neus, Presas‐Rodríguez, Silvia, García‐Robles, Pilar, Montoya, Julio, Ruiz‐Pesini, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2022
Materias:
Short Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543827/
https://www.ncbi.nlm.nih.gov/pubmed/35808913
http://dx.doi.org/10.1111/cge.14189

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