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The Medicines for Malaria Venture Malaria Box contains inhibitors of protein secretion in Plasmodium falciparum blood stage parasites
Plasmodium falciparum parasites which cause malaria, traffic hundreds of proteins into the red blood cells (RBCs) they infect. These exported proteins remodel their RBCs enabling host immune evasion through processes such as cytoadherence that greatly assist parasite survival. As resistance to all c...
Autores principales: | Looker, Oliver, Dans, Madeline G., Bullen, Hayley E., Sleebs, Brad E., Crabb, Brendan S., Gilson, Paul R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons A/S
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543830/ https://www.ncbi.nlm.nih.gov/pubmed/36040075 http://dx.doi.org/10.1111/tra.12862 |
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