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Cell‐to‐cell transmission of HIV‐1 from provirus‐activated cells to resting naïve and memory human primary CD4 T cells is highly efficient and requires CD4 and F‐actin but not chemokine receptors

Latently infected cells harboring replication‐competent proviruses represent a major barrier to HIV‐1 cure. One major effort to purge these cells has focused on developing the “shock and kill” approach for forcing provirus reactivation to induce cell killing by viral cytopathic effects, host immune...

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Detalles Bibliográficos
Autores principales: Lan, Jie, Li, Wei, Yu, Richard, Syed, Fahim, Yu, Qigui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543916/
https://www.ncbi.nlm.nih.gov/pubmed/35840493
http://dx.doi.org/10.1002/jmv.28005

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