The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype

Variant of concern (VOC) Omicron-BA.1 has achieved global predominance in early 2022. Therefore, surveillance and comprehensive characterization of Omicron-BA.1 in advanced primary cell culture systems and animal models are urgently needed. Here, we characterize Omicron-BA.1 and recombinant Omicron-...

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Autores principales: Barut, G. Tuba, Halwe, Nico Joel, Taddeo, Adriano, Kelly, Jenna N., Schön, Jacob, Ebert, Nadine, Ulrich, Lorenz, Devisme, Christelle, Steiner, Silvio, Trüeb, Bettina Salome, Hoffmann, Bernd, Veiga, Inês Berenguer, Leborgne, Nathan Georges François, Moreira, Etori Aguiar, Breithaupt, Angele, Wylezich, Claudia, Höper, Dirk, Wernike, Kerstin, Godel, Aurélie, Thomann, Lisa, Flück, Vera, Stalder, Hanspeter, Brügger, Melanie, Esteves, Blandina I. Oliveira, Zumkehr, Beatrice, Beilleau, Guillaume, Kratzel, Annika, Schmied, Kimberly, Ochsenbein, Sarah, Lang, Reto M., Wider, Manon, Machahua, Carlos, Dorn, Patrick, Marti, Thomas M., Funke-Chambour, Manuela, Rauch, Andri, Widera, Marek, Ciesek, Sandra, Dijkman, Ronald, Hoffmann, Donata, Alves, Marco P., Benarafa, Charaf, Beer, Martin, Thiel, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543931/
https://www.ncbi.nlm.nih.gov/pubmed/36207334
http://dx.doi.org/10.1038/s41467-022-33632-y

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