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Suppression of TGF‐β/Smad2 signaling by GW788388 enhances DENV‐2 clearance in macrophages

Dengue fever, caused by the dengue virus (DENV‐1, −2, −3, and −4), affects millions of people in the tropical and subtropical regions worldwide. Severe dengue is correlated with high viraemia and cytokine storm, such as high levels of transforming growth factor‐β1 (TGF‐β1) in the patient's seru...

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Detalles Bibliográficos
Autores principales: Teixeira, Gabrielly Sbano, Andrade, Audrien Alves, Torres, Lauana Ribas, Couto‐Lima, Dinair, Moreira, Otacilio C., Abreu, Rayane, Waghabi, Mariana Caldas, de Souza, Elen Mello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544077/
https://www.ncbi.nlm.nih.gov/pubmed/35596058
http://dx.doi.org/10.1002/jmv.27879