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The tyrosine kinase inhibitor nilotinib targets the discoidin domain receptor DDR2 in calcific aortic valve stenosis
BACKGROUND AND PURPOSE: Tyrosine kinase inhibitors (TKI) used to treat chronic myeloid leukaemia (CML) have been associated with cardiovascular side effects, including reports of calcific aortic valve stenosis. The aim of this study was to establish the effects of first and second generation TKIs in...
Autores principales: | Carracedo, Miguel, Pawelzik, Sven‐Christian, Artiach, Gonzalo, Pouwer, Marianne G., Plunde, Oscar, Saliba‐Gustafsson, Peter, Ehrenborg, Ewa, Eriksson, Per, Pieterman, Elsbet, Stenke, Leif, Princen, Hans M. G., Franco‐Cereceda, Anders, Bäck, Magnus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544120/ https://www.ncbi.nlm.nih.gov/pubmed/35751904 http://dx.doi.org/10.1111/bph.15911 |
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