Accelerating Brain Imaging Using a Silent Spatial Encoding Axis

PURPOSE: To characterize the acceleration capabilities of a silent head insert gradient axis that operates at the inaudible frequency of 20 kHz and a maximum gradient amplitude of 40 mT/m without inducing peripheral nerve stimulation. METHODS: The silent gradient axis' acquisitions feature an oscillating gradient in the phase‐encoding direction that is played out on top of a cartesian readout, similarly as done in Wave‐CAIPI. The additional spatial encoding fills k‐space in readout lanes allowing for the acquisition of fewer phase‐encoding steps without increasing aliasing artifacts. Fully sampled 2D gradient echo datasets were acquired both with and without the silent readout. All scans were retrospectively undersampled (acceleration factors R = 1 to 12) to compare conventional SENSE acceleration and acceleration using the silent gradient. The silent gradient amplitude and the readout bandwidth were varied to investigate the effect on artifacts and g‐factor. RESULTS: The silent readout reduced the g‐factor for all acceleration factors when compared to SENSE acceleration. Increasing the silent gradient amplitude from 31.5 mT/m to 40 mT/m at an acceleration factor of 10 yielded a reduction in the average g‐factor (g(avg)) from 1.3 ± 0.14 (g(max) = 1.9) to 1.1 ± 0.09 (g(max) = 1.6)(.) Furthermore, reducing the number of cycles increased the readout bandwidth and the g‐factor that reached g(avg) = 1.5 ± 0.16 for a readout bandwidth of 651 Hz/pixel and an acceleration factor of R = 8. CONCLUSION: A silent gradient axis enables high acceleration factors up to R = 10 while maintaining a g‐factor close to unity (g(avg) = 1.1 and g(max) = 1.6) and can be acquired with clinically relevant readout bandwidths.