Augmenting glycosylation‐directed folding pathways enhances the fidelity of HIV Env immunogen production in plants

Heterologous glycoprotein production relies on host glycosylation‐dependent folding. When the biosynthetic machinery differs from the usual expression host, there is scope to remodel the assembly pathway to enhance glycoprotein production. Here we explore the integration of chaperone coexpression wi...

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Detalles Bibliográficos
Autores principales: Margolin, Emmanuel, Allen, Joel D., Verbeek, Matthew, Chapman, Ros, Meyers, Ann, van Diepen, Michiel, Ximba, Phindile, Motlou, Thopisang, Moore, Penny L., Woodward, Jeremy, Strasser, Richard, Crispin, Max, Williamson, Anna‐Lise, Rybicki, Edward P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544252/
https://www.ncbi.nlm.nih.gov/pubmed/35781691
http://dx.doi.org/10.1002/bit.28169

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