Cargando…

Severe COVID-19 induces autoantibodies against angiotensin II that correlate with blood pressure dysregulation and disease severity

Patients infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can experience life-threatening respiratory distress, blood pressure dysregulation, and thrombosis. This is thought to be associated with an impaired activity of angiotensin-converting enzyme 2 (ACE2), which is t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Briquez, Priscilla S., Rouhani, Sherin J., Yu, Jovian, Pyzer, Athalia R., Trujillo, Jonathan, Dugan, Haley L., Stamper, Christopher T., Changrob, Siriruk, Sperling, Anne I., Wilson, Patrick C., Gajewski, Thomas F., Hubbell, Jeffrey A., Swartz, Melody A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544317/ https://www.ncbi.nlm.nih.gov/pubmed/36206332 http://dx.doi.org/10.1126/sciadv.abn3777

Ejemplares similares

SARS-CoV-2 infection induces cross-reactive autoantibodies against angiotensin II
por: Briquez, Priscilla S., et al.
Publicado: (2021)

The Impact of Diabetes and African American Race in COVID-19 Severity
por: Arosemena, Marilyn A, et al.
Publicado: (2021)

Lymphatic coagulation and neutrophil extracellular traps in lung-draining lymph nodes of COVID-19 decedents
por: MacDonald, Margo E., et al.
Publicado: (2022)

Antibody and T cell responses to COVID-19 vaccination in patients receiving anticancer therapies
por: Rouhani, Sherin Juliet, et al.
Publicado: (2022)

Severe hematotoxicity after CD19 CAR-T therapy is associated with suppressive immune dysregulation and limited CAR-T expansion
por: Rejeski, Kai, et al.
Publicado: (2023)

Engineered IL-7 synergizes with IL-12 immunotherapy to prevent T cell exhaustion and promote memory without exacerbating toxicity
por: Kang, Seounghun, et al.
Publicado: (2023)

Rapid, site-specific labeling of “off-the-shelf” and native serum autoantibodies with T cell–redirecting domains
por: Zappala, Fabiana, et al.
Publicado: (2022)

Identification of IgA autoantibodies targeting mesangial cells redefines the pathogenesis of IgA nephropathy
por: Nihei, Yoshihito, et al.
Publicado: (2023)

Complement C3 inhibition in severe COVID-19 using compstatin AMY-101
por: Skendros, Panagiotis, et al.
Publicado: (2022)

CCR2 is a host entry receptor for severe fever with thrombocytopenia syndrome virus
por: Zhang, Leike, et al.
Publicado: (2023)

Systemic inflammation and metabolic disturbances underlie inpatient mortality among ill children with severe malnutrition
por: Wen, Bijun, et al.
Publicado: (2022)

Neurological disorders after severe pneumonia are associated with translocation of endogenous bacteria from the lung to the brain
por: Ma, Qingle, et al.
Publicado: (2023)

Magnitude and kinetics of the human immune cell response associated with severe dengue progression by single-cell proteomics
por: Robinson, Makeda L., et al.
Publicado: (2023)

A systems biology approach identifies candidate drugs to reduce mortality in severely ill patients with COVID-19
por: Fava, Vinicius M., et al.
Publicado: (2022)

Severe acute malnutrition promotes bacterial binding over proinflammatory cytokine secretion by circulating innate immune cells
por: Phiri, Tracy N., et al.
Publicado: (2023)

Skin and heart allograft rejection solely by long-lived alloreactive T(RM) cells in skin of severe combined immunodeficient mice
por: Tian, Qianchuan, et al.
Publicado: (2022)

Large1 gene transfer in older myd mice with severe muscular dystrophy restores muscle function and greatly improves survival
por: Yonekawa, Takahiro, et al.
Publicado: (2022)

PIK3CA gain-of-function mutation in adipose tissue induces metabolic reprogramming with Warburg-like effect and severe endocrine disruption
por: Ladraa, Sophia, et al.
Publicado: (2022)

A widespread length-dependent splicing dysregulation in cancer
por: Zhang, Sirui, et al.
Publicado: (2022)

Divergent cis-regulatory evolution underlies the convergent loss of sodium channel expression in electric fish
por: LaPotin, Sarah, et al.
Publicado: (2022)

Association Between Rheumatic Autoantibodies and Immune-Related Adverse Events
por: Mathias, Kristen, et al.
Publicado: (2023)

Structure of the Shaker Kv channel and mechanism of slow C-type inactivation
por: Tan, Xiao-Feng, et al.
Publicado: (2022)

PI3-kinase deletion promotes myelodysplasia by dysregulating autophagy in hematopoietic stem cells
por: Ames, Kristina, et al.
Publicado: (2023)

CTRP3 exacerbates tendinopathy by dysregulating tendon stem cell differentiation and altering extracellular matrix composition
por: Cho, Yongsik, et al.
Publicado: (2021)

CAGE sequencing reveals CFTR-dependent dysregulation of type I IFN signaling in activated cystic fibrosis macrophages
por: Gillan, Jonathan L., et al.
Publicado: (2023)

Chemokines expressed by engineered bacteria recruit and orchestrate antitumor immunity
por: Savage, Thomas M., et al.
Publicado: (2023)

Engineering Targeting Materials for Therapeutic Cancer Vaccines
por: Briquez, Priscilla S., et al.
Publicado: (2020)

TWIST2-mediated chromatin remodeling promotes fusion-negative rhabdomyosarcoma
por: Shah, Akansha M., et al.
Publicado: (2023)

Critical role of lncEPAT in coupling dysregulated EGFR pathway and histone H2A deubiquitination during glioblastoma tumorigenesis
por: Li, Linlin, et al.
Publicado: (2022)

Podocyte-specific KLF4 is required to maintain parietal epithelial cell quiescence in the kidney
por: Pace, Jesse A., et al.
Publicado: (2021)

Microphysiological model of PIK3CA-driven vascular malformations reveals a role of dysregulated Rac1 and mTORC1/2 in lesion formation
por: Aw, Wen Yih, et al.
Publicado: (2023)

PAI-1 is a vascular cell–specific HIF-2–dependent angiogenic factor that promotes retinal neovascularization in diabetic patients
por: Qin, Yaowu, et al.
Publicado: (2022)

Lectin-Seq: A method to profile lectin-microbe interactions in native communities
por: McPherson, Robert L., et al.
Publicado: (2023)

Comparison of replicating and nonreplicating vaccines against SARS-CoV-2
por: Mudrick, Haley E., et al.
Publicado: (2022)

Lymphangiogenesis-inducing vaccines elicit potent and long-lasting T cell immunity against melanomas
por: Sasso, Maria Stella, et al.
Publicado: (2021)

Checkpoint Blockade–Induced Dermatitis and Colitis Are Dominated by Tissue-Resident Memory T Cells and Th1/Tc1 Cytokines
por: Reschke, Robin, et al.
Publicado: (2022)

Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing
por: Ishihara, Jun, et al.
Publicado: (2018)

Severe COVID-19 infection is associated with aberrant cytokine production by infected lung epithelial cells rather than by systemic immune dysfunction
por: Rouhani, Sherin J, et al.
Publicado: (2021)

Sensing low intracellular potassium by NLRP3 results in a stable open structure that promotes inflammasome activation
por: Tapia-Abellán, Ana, et al.
Publicado: (2021)

Biological resurfacing in a canine model of hip osteoarthritis
por: Estes, Bradley T., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_jd7d7ob8r7m7kk6hv9qjics7en