Distinct roles of ORAI1 in T cell–mediated allergic airway inflammation and immunity to influenza A virus infection

T cell activation and function depend on Ca(2+) signals mediated by store-operated Ca(2+) entry (SOCE) through Ca(2+) release–activated Ca(2+) (CRAC) channels formed by ORAI1 proteins. We here investigated how SOCE controls T cell function in pulmonary inflammation during a T helper 1 (T(H)1) cell–m...

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Detalles Bibliográficos
Autores principales: Wang, Yin-Hu, Noyer, Lucile, Kahlfuss, Sascha, Raphael, Dimitrius, Tao, Anthony Y., Kaufmann, Ulrike, Zhu, Jingjie, Mitchell-Flack, Marisa, Sidhu, Ikjot, Zhou, Fang, Vaeth, Martin, Thomas, Paul G., Saunders, Sean P., Stauderman, Kenneth, Curotto de Lafaille, Maria A., Feske, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544339/
https://www.ncbi.nlm.nih.gov/pubmed/36206339
http://dx.doi.org/10.1126/sciadv.abn6552

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