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Keratosis pilaris rubra successfully treated with topical sirolimus: Report of a case and review of the literature

Keratosis pilaris rubra (KPR) is a subtype of keratosis pilaris (KP) presenting with numerous “grainlike” follicular papules in a background of confluent erythema most often affecting the face and upper extremities with persistence beyond puberty. Treatment has remained challenging with inconsistent...

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Detalles Bibliográficos
Autores principales: Eckburg, Alexandra, Kazemi, Tiana, Maguiness, Sheilagh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544444/
https://www.ncbi.nlm.nih.gov/pubmed/35229903
http://dx.doi.org/10.1111/pde.14963
Descripción
Sumario:Keratosis pilaris rubra (KPR) is a subtype of keratosis pilaris (KP) presenting with numerous “grainlike” follicular papules in a background of confluent erythema most often affecting the face and upper extremities with persistence beyond puberty. Treatment has remained challenging with inconsistent benefit from topical therapies such as emollients, keratolytics, corticosteroids, and retinoids, though case reports documenting success with pulsed dye laser therapy have been found. We present a case of KPR in a 15‐year‐old boy who was successfully treated with topical sirolimus 1% cream.