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Microglial response promotes neurodegeneration in the Ndufs4 KO mouse model of Leigh syndrome

Leigh syndrome is a mitochondrial disease characterized by neurodegeneration, neuroinflammation, and early death. Mice lacking NDUFS4, a mitochondrial complex I subunit (Ndufs4 KO mice), have been established as a good animal model for studying human pathology associated with Leigh syndrome. As the...

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Detalles Bibliográficos
Autores principales:	Aguilar, Kevin, Comes, Gemma, Canal, Carla, Quintana, Albert, Sanz, Elisenda, Hidalgo, Juan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544686/ https://www.ncbi.nlm.nih.gov/pubmed/35770802 http://dx.doi.org/10.1002/glia.24234

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