Low‐dose hydralazine reduces albuminuria and glomerulosclerosis in a mouse model of obesity‐related chronic kidney disease

AIM: To determine, using a mouse model of obesity, whether low‐dose hydralazine prevents obesity‐related chronic kidney disease (CKD). METHODS: From 8 weeks of age, male C57BL/6 mice received a high‐fat diet (HFD) or chow, with or without low‐dose hydralazine (25 mg/L) in drinking water, for 24 week...

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Detalles Bibliográficos
Autores principales: Larkin, Benjamin P., Nguyen, Long T., Hou, Miao, Glastras, Sarah J., Chen, Hui, Faiz, Alen, Chen, Jason, Wang, Rosy, Pollock, Carol A., Saad, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544807/
https://www.ncbi.nlm.nih.gov/pubmed/35635331
http://dx.doi.org/10.1111/dom.14778

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544807/
https://www.ncbi.nlm.nih.gov/pubmed/35635331
http://dx.doi.org/10.1111/dom.14778

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