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Chronic myeloid leukaemia patients at diagnosis and resistant to tyrosine kinase inhibitor therapy display exhausted T‐cell phenotype

The search for novel targets in chronic myeloid leukaemia (CML) is ongoing, to improve treatment efficacy in refractory disease and increase eligibility for tyrosine kinase inhibitor (TKI) discontinuation. Increased frequency of Tregs and effector Tregs was evident at diagnosis, together with increa...

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Detalles Bibliográficos
Autores principales: Harrington, Patrick, Dillon, Richard, Radia, Deepti, McLornan, Donal, Woodley, Claire, Asirvatham, Susan, Raj, Kavita, Curto‐Garcia, Natalia, Saunders, Jamie, Kordasti, Shahram, Harrison, Claire, de Lavallade, Hugues
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544983/
https://www.ncbi.nlm.nih.gov/pubmed/35802024
http://dx.doi.org/10.1111/bjh.18302

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