Discovery and characterization of SARS-CoV-2 reactive and neutralizing antibodies from humanized CAMouse(HG) mice through rapid hybridoma screening and high-throughput single-cell V(D)J sequencing

The coronavirus disease 2019 pandemic has caused more than 532 million infections and 6.3 million deaths to date. The reactive and neutralizing fully human antibodies of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are effective detection tools and therapeutic measures. During SARS-C...

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Detalles Bibliográficos
Autores principales: Yang, Xi, Chi, Hang, Wu, Meng, Wang, Zhenshan, Lang, Qiaoli, Han, Qiuxue, Wang, Xinyue, Liu, Xueqin, Li, Yuanguo, Wang, Xiwen, Huang, Nan, Bi, Jinhao, Liang, Hao, Gao, Yuwei, Zhao, Yongkun, Feng, Na, Yang, Songtao, Wang, Tiecheng, Xia, Xianzhu, Ge, Liangpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545174/
https://www.ncbi.nlm.nih.gov/pubmed/36211410
http://dx.doi.org/10.3389/fimmu.2022.992787

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