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Activation of succinate receptor 1 boosts human mast cell reactivity and allergic bronchoconstriction

BACKGROUND: SUCNR1 is a sensor of extracellular succinate, a Krebs cycle intermediate generated in excess during oxidative stress and has been linked to metabolic regulation and inflammation. While mast cells express SUCNR1, its role in mast cell reactivity and allergic conditions such as asthma rem...

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Detalles Bibliográficos
Autores principales:	Tang, Xiao, Rönnberg, Elin, Säfholm, Jesper, Thulasingam, Madhuranayaki, Trauelsen, Mette, Schwartz, Thue W., Wheelock, Craig E., Dahlén, Sven‐Erik, Nilsson, Gunnar, Haeggström, Jesper Z.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	ORIGINAL ARTICLES
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545225/ https://www.ncbi.nlm.nih.gov/pubmed/35122266 http://dx.doi.org/10.1111/all.15245

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