An induced pluripotent stem cell t(7;12)(q36;p13) acute myeloid leukemia model shows high expression of MNX1 and a block in differentiation of the erythroid and megakaryocytic lineages

Acute myeloid leukemia (AML) results from aberrant hematopoietic processes and these changes are frequently initiated by chromosomal translocations. One particular subtype, AML with translocation t(7;12)(q36;p13), is found in children diagnosed before 2 years of age. The mechanisms for leukemogenesi...

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Detalles Bibliográficos
Autores principales: Nilsson, Tina, Waraky, Ahmed, Östlund, Anders, Li, Susann, Staffas, Anna, Asp, Julia, Fogelstrand, Linda, Abrahamsson, Jonas, Palmqvist, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Innovative Tools and Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545334/
https://www.ncbi.nlm.nih.gov/pubmed/35583991
http://dx.doi.org/10.1002/ijc.34122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545334/
https://www.ncbi.nlm.nih.gov/pubmed/35583991
http://dx.doi.org/10.1002/ijc.34122

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