Cargando…

Predictive value of chromosome 18q11.2‐q12.1 loss for benefit from bevacizumab in metastatic colorectal cancer: A post hoc analysis of the randomized phase III‐trial AGITG‐MAX

The VEGF‐A monoclonal antibody bevacizumab is currently recommended for first‐line treatment of all metastatic colorectal cancer (mCRC) patients. Cost‐benefit ratio and side‐effects however necessitate patient selection. A large retrospective yet nonrandomized study showed that patients with loss of...

Descripción completa

Detalles Bibliográficos
Autores principales:	van Dijk, Erik, van Werkhoven, Erik, Asher, Rebecca, Mooi, Jennifer K., Espinoza, David, van Essen, Hendrik F., van Tinteren, Harm, van Grieken, Nicole C. T., Punt, Cornelis J. A., Tebbutt, Niall C., Ylstra, Bauke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2022
Materias:	Tumor Markers and Signatures
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545440/ https://www.ncbi.nlm.nih.gov/pubmed/35489024 http://dx.doi.org/10.1002/ijc.34061

Ejemplares similares

Circulating tumor DNA quantity is related to tumor volume and both predict survival in metastatic pancreatic ductal adenocarcinoma
por: Strijker, Marin, et al.
Publicado: (2019)

The WID‐qEC test: Performance in a hospital‐based cohort and feasibility to detect endometrial and cervical cancers
por: Schreiberhuber, Lena, et al.
Publicado: (2022)

Prediction of clinical benefit from androgen deprivation therapy in salivary duct carcinoma patients
por: van Boxtel, Wim, et al.
Publicado: (2019)

Capturing colorectal cancer inter‐tumor heterogeneity in patient‐derived xenograft (PDX) models
por: Prasetyanti, Pramudita R., et al.
Publicado: (2018)

Ovarian cancer‐derived copy number alterations signatures are prognostic in chemoradiotherapy‐treated head and neck squamous cell carcinoma
por: Essers, Paul B.M., et al.
Publicado: (2020)

Characterisation of anal intraepithelial neoplasia and anal cancer in HIV‐positive men by immunohistochemical markers p16, Ki‐67, HPV‐E4 and DNA methylation markers
por: van der Zee, Ramon P., et al.
Publicado: (2021)

Serum levels of iCAF‐derived osteoglycin predict favorable outcome in pancreatic cancer
por: Dings, Mark P. G., et al.
Publicado: (2022)

DNA methylation markers as triage test for the early identification of cervical lesions in a Chinese population
por: Li, Na, et al.
Publicado: (2020)

IGF‐1R pathway activation as putative biomarker for linsitinib therapy to revert tamoxifen resistance in ER‐positive breast cancer
por: Kruger, Dinja T., et al.
Publicado: (2019)

Genome‐wide microRNA analysis of HPV‐positive self‐samples yields novel triage markers for early detection of cervical cancer
por: Snoek, Barbara C., et al.
Publicado: (2018)

Decreased RORC expression and downstream signaling in HTLV‐1‐associated adult T‐cell lymphoma/leukemia uncovers an antiproliferative IL17 link: A potential target for immunotherapy?
por: Subramanian, Kritika, et al.
Publicado: (2018)

Vesicle‐bound EBV‐BART13‐3p miRNA in circulation distinguishes nasopharyngeal from other head and neck cancer and asymptomatic EBV‐infections
por: Ramayanti, Octavia, et al.
Publicado: (2018)

Clinical and molecular characteristics of estrogen receptor‐positive ultralow risk breast cancer tumors identified by the 70‐gene signature
por: Johansson, Annelie, et al.
Publicado: (2022)

Evaluation of a validated methylation triage signature for human papillomavirus positive women in the HPV FOCAL cervical cancer screening trial
por: Cook, Darrel A., et al.
Publicado: (2018)

Classification of high‐grade cervical intraepithelial neoplasia by p16(ink4a), Ki‐67, HPV E4 and FAM19A4/miR124‐2 methylation status demonstrates considerable heterogeneity with potential consequences for management
por: Vink, Frederique J., et al.
Publicado: (2021)

FAM19A4/miR124‐2 methylation in invasive cervical cancer: A retrospective cross‐sectional worldwide study
por: Vink, Frederique J., et al.
Publicado: (2019)

High hemoglobin A1c levels within the non‐diabetic range are associated with the risk of all cancers
por: Goto, Atsushi, et al.
Publicado: (2015)

High‐resolution imaging for the detection and characterisation of circulating tumour cells from patients with oesophageal, hepatocellular, thyroid and ovarian cancers
por: Dent, Barry M., et al.
Publicado: (2015)

Protein Z: A putative novel biomarker for early detection of ovarian cancer
por: Russell, Matthew R., et al.
Publicado: (2016)

Increased breast cancer screening and downstaging in Colombian women: A randomized trial of opportunistic breast‐screening
por: Murillo, Raúl, et al.
Publicado: (2015)

Validation of a DNA methylation HPV triage classifier in a screening sample
por: Lorincz, Attila T., et al.
Publicado: (2016)

The genetic tumor background is an important determinant for heterogeneous MYCN‐amplified neuroblastoma
por: Bogen, Dominik, et al.
Publicado: (2016)

Distinct and shared three‐dimensional chromosome organization patterns in lymphocytes, monoclonal gammopathy of undetermined significance and multiple myeloma
por: Sathitruangsak, Chirawadee, et al.
Publicado: (2016)

Epstein‐Barr virus mRNA profiles and viral DNA methylation status in nasopharyngeal brushings from nasopharyngeal carcinoma patients reflect tumor origin
por: Ramayanti, Octavia, et al.
Publicado: (2016)

Vitronectin and dermcidin serum levels predict the metastatic progression of AJCC I–II early‐stage melanoma
por: Ortega‐Martínez, Idoia, et al.
Publicado: (2016)

Heat shock protein 70 and tumor‐infiltrating NK cells as prognostic indicators for patients with squamous cell carcinoma of the head and neck after radiochemotherapy: A multicentre retrospective study of the German Cancer Consortium Radiation Oncology Group (DKTK‐ROG)
por: Stangl, Stefan, et al.
Publicado: (2017)

Whole blood FPR1 mRNA expression predicts both non‐small cell and small cell lung cancer
por: Morris, Scott, et al.
Publicado: (2018)

Intraductal papillary mucinous neoplasm of the pancreas rapidly xenografts in chicken eggs and predicts aggressiveness
por: Zhao, Zhefu, et al.
Publicado: (2017)

Assessment of early response biomarkers in relation to long‐term survival in patients with HER2‐negative breast cancer receiving neoadjuvant chemotherapy plus bevacizumab: Results from the Phase II PROMIX trial
por: Kimbung, Siker, et al.
Publicado: (2017)

Transcriptional variations in the wider peritumoral tissue environment of pancreatic cancer
por: Bauer, Andrea S., et al.
Publicado: (2017)

Genomic alterations in plasma DNA from patients with metastasized prostate cancer receiving abiraterone or enzalutamide
por: Belic, Jelena, et al.
Publicado: (2018)

Cancer‐associated fecal microbial markers in colorectal cancer detection
por: Eklöf, Vincy, et al.
Publicado: (2017)

Role of quantitative p16(INK4A) mRNA assay and digital reading of p16(INK4A) immunostained sections in diagnosis of cervical intraepithelial neoplasia
por: Vasiljević, Nataša, et al.
Publicado: (2017)

Long noncoding RNA MIR31HG is a bona fide prognostic marker with colorectal cancer cell‐intrinsic properties
por: Eide, Peter W., et al.
Publicado: (2019)

Clinical significance of circulating tumor cells in predicting disease progression and chemotherapy resistance in patients with gestational choriocarcinoma
por: He, Weiling, et al.
Publicado: (2018)

Alternative splicing expands the prognostic impact of KRAS in microsatellite stable primary colorectal cancer
por: Eilertsen, Ina A., et al.
Publicado: (2018)

Combined genetic and epigenetic alterations of the TERT promoter affect clinical and biological behavior of bladder cancer
por: Leão, Ricardo, et al.
Publicado: (2018)

Toward a real liquid biopsy in metastatic breast and prostate cancer: Diagnostic LeukApheresis increases CTC yields in a European prospective multicenter study (CTCTrap)
por: Andree, Kiki C., et al.
Publicado: (2018)

Profiles of brain metastases: Prioritization of therapeutic targets
por: Ferguson, Sherise D., et al.
Publicado: (2018)

Contribution of upregulated dipeptidyl peptidase 9 (DPP9) in promoting tumoregenicity, metastasis and the prediction of poor prognosis in non‐small cell lung cancer (NSCLC)
por: Tang, Zhiyuan, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_8jnto0j7absokktfat9mket9gb