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Association of lithocholic acid with skeletal muscle hypertrophy through TGR5-IGF-1 and skeletal muscle mass in cultured mouse myotubes, chronic liver disease rats and humans

BACKGROUND: Hepatic sarcopenia is one of many complications associated with chronic liver disease (CLD) and has a high mortality rate; however, the liver-muscle axis is not fully understood. Therefore, few effective treatments exist for hepatic sarcopenia, the best of which being branched-chain amin...

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Detalles Bibliográficos
Autores principales:	Tamai, Yasuyuki, Eguchi, Akiko, Shigefuku, Ryuta, Kitamura, Hiroshi, Tempaku, Mina, Sugimoto, Ryosuke, Kobayashi, Yoshinao, Iwasa, Motoh, Takei, Yoshiyuki, Nakagawa, Hayato
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545520/ https://www.ncbi.nlm.nih.gov/pubmed/36206032 http://dx.doi.org/10.7554/eLife.80638

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