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A phase I/II study of ivaltinostat combined with gemcitabine and erlotinib in patients with untreated locally advanced or metastatic pancreatic adenocarcinoma

This phase I/II study evaluated the safety and efficacy of a new histone deacetylase (HDAC) inhibitor, ivaltinostat, in combination with gemcitabine and erlotinib for advanced pancreatic ductal adenocarcinoma (PDAC). Patients diagnosed with unresectable, histologically confirmed PDAC who had not und...

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Detalles Bibliográficos
Autores principales: Jo, Jung Hyun, Jung, Dawoon E., Lee, Hee Seung, Park, Soo Been, Chung, Moon Jae, Park, Jeong Youp, Bang, Seungmin, Park, Seung Woo, Cho, Sangsook, Song, Si Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545559/
https://www.ncbi.nlm.nih.gov/pubmed/35657348
http://dx.doi.org/10.1002/ijc.34144