Cargando…

Bumetanide for neonatal seizures: No light in the pharmacokinetic/dynamic tunnel

In his editorial, Kevin Staley criticizes our recent work demonstrating the lack of effect of bumetanide in a novel model of neonatal seizures. The main points in our response are that (1) our work is on an asphyxia model, not one on "hypercarbia only"; (2) clinically relevant parenteral d...

Descripción completa

Detalles Bibliográficos
Autores principales: Kaila, Kai, Löscher, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545618/
https://www.ncbi.nlm.nih.gov/pubmed/35524446
http://dx.doi.org/10.1111/epi.17279