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Bacterial Butyrate in Parkinson's Disease Is Linked to Epigenetic Changes and Depressive Symptoms

BACKGROUND: The gut microbiome and its metabolites can impact brain health and are altered in Parkinson's disease (PD) patients. It has been recently demonstrated that PD patients have reduced fecal levels of the potent epigenetic modulator butyrate and its bacterial producers. OBJECTIVES: Here...

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Detalles Bibliográficos
Autores principales: Xie, Aoji, Ensink, Elizabeth, Li, Peipei, Gordevičius, Juozas, Marshall, Lee L., George, Sonia, Pospisilik, John Andrew, Aho, Velma T.E., Houser, Madelyn C., Pereira, Pedro A.B., Rudi, Knut, Paulin, Lars, Tansey, Malú G., Auvinen, Petri, Brundin, Patrik, Brundin, Lena, Labrie, Viviane, Scheperjans, Filip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545646/
https://www.ncbi.nlm.nih.gov/pubmed/35723531
http://dx.doi.org/10.1002/mds.29128