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Targeting the DNA repair enzymes MTH1 and OGG1 as a novel approach to treat inflammatory diseases
Autoimmune diseases and acute inflammation like sepsis cause significant morbidity and disability globally, and new targeted therapies are urgently needed. DNA repair and reactive oxygen species (ROS) pathways have long been investigated as targets for cancer treatment, but their role in immunologic...
Autor principal: | Karsten, Stella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545756/ https://www.ncbi.nlm.nih.gov/pubmed/35708697 http://dx.doi.org/10.1111/bcpt.13765 |
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