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Integrative analysis of genomic and transcriptomic data of normal, tumour, and co‐occurring leukoplakia tissue triads drawn from patients with gingivobuccal oral cancer identifies signatures of tumour initiation and progression

A thickened, white patch — leukoplakia — in the oral cavity is usually benign, but sometimes (in ~9% of individuals) it progresses to malignant tumour. Because the genomic basis of this progression is poorly understood, we undertook this study and collected samples of four tissues — leukoplakia, tum...

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Detalles Bibliográficos
Autores principales: Ghosh, Arnab, Das, Chitrarpita, Ghose, Sandip, Maitra, Arindam, Roy, Bidyut, Majumder, Partha P., Biswas, Nidhan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545831/
https://www.ncbi.nlm.nih.gov/pubmed/35358331
http://dx.doi.org/10.1002/path.5900