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Interaction between mesenchymal stem cells and myoblasts in the context of facioscapulohumeral muscular dystrophy contributes to the disease phenotype

Facioscapulohumeral muscular dystrophy (FSHD) is a genetic disease associated with ectopic expression of the DUX4 gene in skeletal muscle. Muscle degeneration in FSHD is accompanied by muscle tissue replacement with fat and connective tissue. Expression of DUX4 in myoblasts stimulates mesenchymal st...

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Detalles Bibliográficos
Autores principales: Kiseleva, Ekaterina, Serbina, Olesya, Karpukhina, Anna, Mouly, Vincent, Vassetzky, Yegor S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545833/
https://www.ncbi.nlm.nih.gov/pubmed/35621301
http://dx.doi.org/10.1002/jcp.30789

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