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Type 1 diabetes in Laos, 2016–2021

OBJECTIVE: Before 2016, no child was known to survive type 1 diabetes (T1D) in Laos, a lower‐middle income country (LMIC) in South‐east Asia. In partnership with the Laos government, a non‐government organization (NGO) called Action4Diabetes (A4D) has since been providing insulin, blood glucose moni...

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Autores principales: Lek, Ngee, Manivong, Amphayvanh, Rassavong, Khaysy, Phommachack, Daoheuang, Toomey, Charles, Ng, Sze May
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons A/S 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545879/
https://www.ncbi.nlm.nih.gov/pubmed/35598163
http://dx.doi.org/10.1111/pedi.13366
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author Lek, Ngee
Manivong, Amphayvanh
Rassavong, Khaysy
Phommachack, Daoheuang
Toomey, Charles
Ng, Sze May
author_facet Lek, Ngee
Manivong, Amphayvanh
Rassavong, Khaysy
Phommachack, Daoheuang
Toomey, Charles
Ng, Sze May
author_sort Lek, Ngee
collection PubMed
description OBJECTIVE: Before 2016, no child was known to survive type 1 diabetes (T1D) in Laos, a lower‐middle income country (LMIC) in South‐east Asia. In partnership with the Laos government, a non‐government organization (NGO) called Action4Diabetes (A4D) has since been providing insulin, blood glucose monitoring kits, HbA1c testing, and emergency hospital expenses for Laotian children and young people (CYP) with T1D, and education for healthcare professionals. Here, we report the demographics and clinical outcomes of the CYP with T1D enrolled in A4D's Clinic Support Programme. RESEARCH DESIGN AND METHODS: We collated and analyzed data on all known CYP with T1D in Laos, including gender, age and presentation at diagnosis, duration of diabetes, hospital admissions, and glycemic control during follow‐up. RESULTS: Fifty‐three CYP (30 male; 57%) were diagnosed with T1D at a mean age of 11.3 years. Thirty CYP (57%) presented in diabetic ketoacidosis (DKA) at diagnosis. As at 16 August 2021, mean duration of T1D was 2.3 years. Forty‐five CYP (85%) remained on active follow‐up. Mean HbA1c for all 53 CYP was 8.7% (72 mmol/mol). Average HbA1c for the CYP in the age ranges of 1–5 years, 6–10 years, 11–15 years, 16–20 years, and 21–25 years, was 7.9% (63 mmol/mol), 8.2% (66), 8.4% (68), 9.4% (79), and 8.4% (68), respectively. CONCLUSIONS: This is the first report on the status of T1D care in Laos, achieved through close partnership between the government and an NGO from 2016 to 2021. More global efforts to improve T1D care outcomes in Laos and other LMICs are urgently needed.
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spelling pubmed-95458792022-10-14 Type 1 diabetes in Laos, 2016–2021 Lek, Ngee Manivong, Amphayvanh Rassavong, Khaysy Phommachack, Daoheuang Toomey, Charles Ng, Sze May Pediatr Diabetes Epidemiology OBJECTIVE: Before 2016, no child was known to survive type 1 diabetes (T1D) in Laos, a lower‐middle income country (LMIC) in South‐east Asia. In partnership with the Laos government, a non‐government organization (NGO) called Action4Diabetes (A4D) has since been providing insulin, blood glucose monitoring kits, HbA1c testing, and emergency hospital expenses for Laotian children and young people (CYP) with T1D, and education for healthcare professionals. Here, we report the demographics and clinical outcomes of the CYP with T1D enrolled in A4D's Clinic Support Programme. RESEARCH DESIGN AND METHODS: We collated and analyzed data on all known CYP with T1D in Laos, including gender, age and presentation at diagnosis, duration of diabetes, hospital admissions, and glycemic control during follow‐up. RESULTS: Fifty‐three CYP (30 male; 57%) were diagnosed with T1D at a mean age of 11.3 years. Thirty CYP (57%) presented in diabetic ketoacidosis (DKA) at diagnosis. As at 16 August 2021, mean duration of T1D was 2.3 years. Forty‐five CYP (85%) remained on active follow‐up. Mean HbA1c for all 53 CYP was 8.7% (72 mmol/mol). Average HbA1c for the CYP in the age ranges of 1–5 years, 6–10 years, 11–15 years, 16–20 years, and 21–25 years, was 7.9% (63 mmol/mol), 8.2% (66), 8.4% (68), 9.4% (79), and 8.4% (68), respectively. CONCLUSIONS: This is the first report on the status of T1D care in Laos, achieved through close partnership between the government and an NGO from 2016 to 2021. More global efforts to improve T1D care outcomes in Laos and other LMICs are urgently needed. John Wiley & Sons A/S 2022-06-06 2022-09 /pmc/articles/PMC9545879/ /pubmed/35598163 http://dx.doi.org/10.1111/pedi.13366 Text en © 2022 The Authors. Pediatric Diabetes published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Epidemiology
Lek, Ngee
Manivong, Amphayvanh
Rassavong, Khaysy
Phommachack, Daoheuang
Toomey, Charles
Ng, Sze May
Type 1 diabetes in Laos, 2016–2021
title Type 1 diabetes in Laos, 2016–2021
title_full Type 1 diabetes in Laos, 2016–2021
title_fullStr Type 1 diabetes in Laos, 2016–2021
title_full_unstemmed Type 1 diabetes in Laos, 2016–2021
title_short Type 1 diabetes in Laos, 2016–2021
title_sort type 1 diabetes in laos, 2016–2021
topic Epidemiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545879/
https://www.ncbi.nlm.nih.gov/pubmed/35598163
http://dx.doi.org/10.1111/pedi.13366
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