Cargando…
Self‐reporting and screening: Data with right‐censored, left‐censored, and complete observations
We consider survival data that combine three types of observations: uncensored, right‐censored, and left‐censored. Such data arises from screening a medical condition, in situations where self‐detection arises naturally. Our goal is to estimate the failure‐time distribution, based on these three obs...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546051/ https://www.ncbi.nlm.nih.gov/pubmed/35608143 http://dx.doi.org/10.1002/sim.9434 |
_version_ | 1784804956411265024 |
---|---|
author | Yefenof, Jonathan Goldberg, Yair Wiler, Jennifer Mandelbaum, Avishai Ritov, Ya'acov |
author_facet | Yefenof, Jonathan Goldberg, Yair Wiler, Jennifer Mandelbaum, Avishai Ritov, Ya'acov |
author_sort | Yefenof, Jonathan |
collection | PubMed |
description | We consider survival data that combine three types of observations: uncensored, right‐censored, and left‐censored. Such data arises from screening a medical condition, in situations where self‐detection arises naturally. Our goal is to estimate the failure‐time distribution, based on these three observation types. We propose a novel methodology for distribution estimation using both semiparametric and nonparametric techniques. We then evaluate the performance of these estimators via simulated data. Finally, as a case study, we estimate the patience of patients who arrive at an emergency department and wait for treatment. Three categories of patients are observed: those who leave the system and announce it, and thus their patience time is observed; those who get service and thus their patience time is right‐censored by the waiting time; and those who leave the system without announcing it. For this third category, the patients' absence is revealed only when they are called to service, which is after they have already left; formally, their patience time is left‐censored. Other applications of our proposed methodology are discussed. |
format | Online Article Text |
id | pubmed-9546051 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-95460512022-10-14 Self‐reporting and screening: Data with right‐censored, left‐censored, and complete observations Yefenof, Jonathan Goldberg, Yair Wiler, Jennifer Mandelbaum, Avishai Ritov, Ya'acov Stat Med Research Articles We consider survival data that combine three types of observations: uncensored, right‐censored, and left‐censored. Such data arises from screening a medical condition, in situations where self‐detection arises naturally. Our goal is to estimate the failure‐time distribution, based on these three observation types. We propose a novel methodology for distribution estimation using both semiparametric and nonparametric techniques. We then evaluate the performance of these estimators via simulated data. Finally, as a case study, we estimate the patience of patients who arrive at an emergency department and wait for treatment. Three categories of patients are observed: those who leave the system and announce it, and thus their patience time is observed; those who get service and thus their patience time is right‐censored by the waiting time; and those who leave the system without announcing it. For this third category, the patients' absence is revealed only when they are called to service, which is after they have already left; formally, their patience time is left‐censored. Other applications of our proposed methodology are discussed. John Wiley and Sons Inc. 2022-05-24 2022-08-15 /pmc/articles/PMC9546051/ /pubmed/35608143 http://dx.doi.org/10.1002/sim.9434 Text en © 2022 The Authors. Statistics in Medicine published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Articles Yefenof, Jonathan Goldberg, Yair Wiler, Jennifer Mandelbaum, Avishai Ritov, Ya'acov Self‐reporting and screening: Data with right‐censored, left‐censored, and complete observations |
title | Self‐reporting and screening: Data with right‐censored, left‐censored, and complete observations |
title_full | Self‐reporting and screening: Data with right‐censored, left‐censored, and complete observations |
title_fullStr | Self‐reporting and screening: Data with right‐censored, left‐censored, and complete observations |
title_full_unstemmed | Self‐reporting and screening: Data with right‐censored, left‐censored, and complete observations |
title_short | Self‐reporting and screening: Data with right‐censored, left‐censored, and complete observations |
title_sort | self‐reporting and screening: data with right‐censored, left‐censored, and complete observations |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546051/ https://www.ncbi.nlm.nih.gov/pubmed/35608143 http://dx.doi.org/10.1002/sim.9434 |
work_keys_str_mv | AT yefenofjonathan selfreportingandscreeningdatawithrightcensoredleftcensoredandcompleteobservations AT goldbergyair selfreportingandscreeningdatawithrightcensoredleftcensoredandcompleteobservations AT wilerjennifer selfreportingandscreeningdatawithrightcensoredleftcensoredandcompleteobservations AT mandelbaumavishai selfreportingandscreeningdatawithrightcensoredleftcensoredandcompleteobservations AT ritovyaacov selfreportingandscreeningdatawithrightcensoredleftcensoredandcompleteobservations |