Polypyrimidine tract binding protein 1 regulates the activation of mouse CD8 T cells

The RNA‐binding protein polypyrimidine tract binding protein 1 (PTBP1) has been found to have roles in CD4 T‐cell activation, but its function in CD8 T cells remains untested. We show it is dispensable for the development of naïve mouse CD8 T cells, but is necessary for the optimal expansion and pro...

Descripción completa

Detalles Bibliográficos
Autores principales: D'Angeli, Vanessa, Monzón‐Casanova, Elisa, Matheson, Louise S., Gizlenci, Özge, Petkau, Georg, Gooding, Clare, Berrens, Rebecca V., Smith, Christopher W. J., Turner, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Adaptive immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546061/
https://www.ncbi.nlm.nih.gov/pubmed/35460072
http://dx.doi.org/10.1002/eji.202149781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546061/
https://www.ncbi.nlm.nih.gov/pubmed/35460072
http://dx.doi.org/10.1002/eji.202149781

Ejemplares similares