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Six‐year‐old children had greater risks of functional gastrointestinal disorders if their parents had mental health conditions

AIM: This study examined any associations between parents' mental health conditions and hospital diagnoses of functional gastrointestinal disorders (FGIDs) in offspring at the age of six. We also examined any associations between children who met these criteria and attended routine Danish preve...

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Autores principales: Heuckendorff, Signe, Johansen, Martin Nygård, Overgaard, Charlotte, Johnsen, Søren Paaske, Thomsen, Janus Laust, Fonager, Kirsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546162/
https://www.ncbi.nlm.nih.gov/pubmed/35726689
http://dx.doi.org/10.1111/apa.16459
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author Heuckendorff, Signe
Johansen, Martin Nygård
Overgaard, Charlotte
Johnsen, Søren Paaske
Thomsen, Janus Laust
Fonager, Kirsten
author_facet Heuckendorff, Signe
Johansen, Martin Nygård
Overgaard, Charlotte
Johnsen, Søren Paaske
Thomsen, Janus Laust
Fonager, Kirsten
author_sort Heuckendorff, Signe
collection PubMed
description AIM: This study examined any associations between parents' mental health conditions and hospital diagnoses of functional gastrointestinal disorders (FGIDs) in offspring at the age of six. We also examined any associations between children who met these criteria and attended routine Danish preventive child health appointments. METHODS: Nationwide registers identified all children born in Denmark from 2000 to 2011 and parents' mental health conditions. Negative binomial regression analyses estimated the incidence rate ratios (IRRs) with 95% confidence intervals (CIs) of children receiving their first hospital diagnosis for an FGID at the age of six. RESULTS: We identified 750,379 children and 38% had at least one parent with a mental health condition: 24% were minor, 12% were moderate, and 2% were severe. These children faced a higher risk of an FGID diagnosis than children whose parents did not have mental health conditions. The IRRs were highest for maternal exposure: minor (1.35, 95% CI 1.29–1.42), moderate (1.58, 95% CI 1.48–1.67) and severe (1.58, 95% CI 1.38–1.81). Attending routine preventive child health examinations was associated with a higher risk of FGIDs associated with parents' mental health conditions. CONCLUSION: Paediatric FGIDs were associated with parents' mental health conditions, especially mothers, and attending routine preventive child health examinations.
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spelling pubmed-95461622022-10-14 Six‐year‐old children had greater risks of functional gastrointestinal disorders if their parents had mental health conditions Heuckendorff, Signe Johansen, Martin Nygård Overgaard, Charlotte Johnsen, Søren Paaske Thomsen, Janus Laust Fonager, Kirsten Acta Paediatr Original Articles & Brief Reports AIM: This study examined any associations between parents' mental health conditions and hospital diagnoses of functional gastrointestinal disorders (FGIDs) in offspring at the age of six. We also examined any associations between children who met these criteria and attended routine Danish preventive child health appointments. METHODS: Nationwide registers identified all children born in Denmark from 2000 to 2011 and parents' mental health conditions. Negative binomial regression analyses estimated the incidence rate ratios (IRRs) with 95% confidence intervals (CIs) of children receiving their first hospital diagnosis for an FGID at the age of six. RESULTS: We identified 750,379 children and 38% had at least one parent with a mental health condition: 24% were minor, 12% were moderate, and 2% were severe. These children faced a higher risk of an FGID diagnosis than children whose parents did not have mental health conditions. The IRRs were highest for maternal exposure: minor (1.35, 95% CI 1.29–1.42), moderate (1.58, 95% CI 1.48–1.67) and severe (1.58, 95% CI 1.38–1.81). Attending routine preventive child health examinations was associated with a higher risk of FGIDs associated with parents' mental health conditions. CONCLUSION: Paediatric FGIDs were associated with parents' mental health conditions, especially mothers, and attending routine preventive child health examinations. John Wiley and Sons Inc. 2022-07-03 2022-10 /pmc/articles/PMC9546162/ /pubmed/35726689 http://dx.doi.org/10.1111/apa.16459 Text en © 2022 The Authors. Acta Paediatrica published by John Wiley & Sons Ltd on behalf of Foundation Acta Paediatrica. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Articles & Brief Reports
Heuckendorff, Signe
Johansen, Martin Nygård
Overgaard, Charlotte
Johnsen, Søren Paaske
Thomsen, Janus Laust
Fonager, Kirsten
Six‐year‐old children had greater risks of functional gastrointestinal disorders if their parents had mental health conditions
title Six‐year‐old children had greater risks of functional gastrointestinal disorders if their parents had mental health conditions
title_full Six‐year‐old children had greater risks of functional gastrointestinal disorders if their parents had mental health conditions
title_fullStr Six‐year‐old children had greater risks of functional gastrointestinal disorders if their parents had mental health conditions
title_full_unstemmed Six‐year‐old children had greater risks of functional gastrointestinal disorders if their parents had mental health conditions
title_short Six‐year‐old children had greater risks of functional gastrointestinal disorders if their parents had mental health conditions
title_sort six‐year‐old children had greater risks of functional gastrointestinal disorders if their parents had mental health conditions
topic Original Articles & Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546162/
https://www.ncbi.nlm.nih.gov/pubmed/35726689
http://dx.doi.org/10.1111/apa.16459
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