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Association between body mass index and varicocele among 211 989 Chinese reproductive‐age males

OBJECTIVES: To explore the relationship between body mass index and varicocele, the range of body mass index that leads to increased odds of varicocele, and the association between body mass index with the position and grade of varicocele. METHODS: We conducted a cross‐sectional study of 211 989 Chi...

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Autores principales: Hu, Xuhuai, Yang, Xueying, Zhao, Jun, Guan, Ting, Dai, Qiaoyun, Yang, Juan, Zhang, Hongguang, Zhang, Dongmei, Zhang, Yue, Shang, Li, Ma, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546267/
https://www.ncbi.nlm.nih.gov/pubmed/35483962
http://dx.doi.org/10.1111/iju.14915
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author Hu, Xuhuai
Yang, Xueying
Zhao, Jun
Guan, Ting
Dai, Qiaoyun
Yang, Juan
Zhang, Hongguang
Zhang, Dongmei
Zhang, Yue
Shang, Li
Ma, Xu
author_facet Hu, Xuhuai
Yang, Xueying
Zhao, Jun
Guan, Ting
Dai, Qiaoyun
Yang, Juan
Zhang, Hongguang
Zhang, Dongmei
Zhang, Yue
Shang, Li
Ma, Xu
author_sort Hu, Xuhuai
collection PubMed
description OBJECTIVES: To explore the relationship between body mass index and varicocele, the range of body mass index that leads to increased odds of varicocele, and the association between body mass index with the position and grade of varicocele. METHODS: We conducted a cross‐sectional study of 211 989 Chinese males aged 18–65 years participated in the National Free Pre‐conception Check‐up Projects from January 2013 to December 2018. Univariate and multivariate logistic regression models were constructed to assess the association between body mass index and varicocele. RESULTS: Overweight and obese males had 13.1% (odds ratio 0.869, 95% confidence interval 0.838–0.902) and 32.3% (odds ratio 0.677, 95% confidence interval 0.632–0.725) lower odds of varicocele than those with normal body mass index, respectively. The association between them was non‐linear, and males with body mass index of 17.74 to 23.09 kg/m(2) had an increased odds of varicocele. The overweight and obese males had lower odds of left and bilateral varicocele, but the right varicocele odds was increased by 63.3% in obese males. CONCLUSION: Body mass index was associated with the odds of varicocele among reproductive‐age males, but the odds varied by position. The effects of weight management and varicocele on fertility should be taken into account in fertility guidance.
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spelling pubmed-95462672022-10-14 Association between body mass index and varicocele among 211 989 Chinese reproductive‐age males Hu, Xuhuai Yang, Xueying Zhao, Jun Guan, Ting Dai, Qiaoyun Yang, Juan Zhang, Hongguang Zhang, Dongmei Zhang, Yue Shang, Li Ma, Xu Int J Urol Original Articles: Clinical Investigation OBJECTIVES: To explore the relationship between body mass index and varicocele, the range of body mass index that leads to increased odds of varicocele, and the association between body mass index with the position and grade of varicocele. METHODS: We conducted a cross‐sectional study of 211 989 Chinese males aged 18–65 years participated in the National Free Pre‐conception Check‐up Projects from January 2013 to December 2018. Univariate and multivariate logistic regression models were constructed to assess the association between body mass index and varicocele. RESULTS: Overweight and obese males had 13.1% (odds ratio 0.869, 95% confidence interval 0.838–0.902) and 32.3% (odds ratio 0.677, 95% confidence interval 0.632–0.725) lower odds of varicocele than those with normal body mass index, respectively. The association between them was non‐linear, and males with body mass index of 17.74 to 23.09 kg/m(2) had an increased odds of varicocele. The overweight and obese males had lower odds of left and bilateral varicocele, but the right varicocele odds was increased by 63.3% in obese males. CONCLUSION: Body mass index was associated with the odds of varicocele among reproductive‐age males, but the odds varied by position. The effects of weight management and varicocele on fertility should be taken into account in fertility guidance. John Wiley and Sons Inc. 2022-04-28 2022-08 /pmc/articles/PMC9546267/ /pubmed/35483962 http://dx.doi.org/10.1111/iju.14915 Text en © 2022 The Authors. International Journal of Urology published by John Wiley & Sons Australia, Ltd on behalf of The Japanese Urological Association. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Articles: Clinical Investigation
Hu, Xuhuai
Yang, Xueying
Zhao, Jun
Guan, Ting
Dai, Qiaoyun
Yang, Juan
Zhang, Hongguang
Zhang, Dongmei
Zhang, Yue
Shang, Li
Ma, Xu
Association between body mass index and varicocele among 211 989 Chinese reproductive‐age males
title Association between body mass index and varicocele among 211 989 Chinese reproductive‐age males
title_full Association between body mass index and varicocele among 211 989 Chinese reproductive‐age males
title_fullStr Association between body mass index and varicocele among 211 989 Chinese reproductive‐age males
title_full_unstemmed Association between body mass index and varicocele among 211 989 Chinese reproductive‐age males
title_short Association between body mass index and varicocele among 211 989 Chinese reproductive‐age males
title_sort association between body mass index and varicocele among 211 989 chinese reproductive‐age males
topic Original Articles: Clinical Investigation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546267/
https://www.ncbi.nlm.nih.gov/pubmed/35483962
http://dx.doi.org/10.1111/iju.14915
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