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Association between body mass index and varicocele among 211 989 Chinese reproductive‐age males
OBJECTIVES: To explore the relationship between body mass index and varicocele, the range of body mass index that leads to increased odds of varicocele, and the association between body mass index with the position and grade of varicocele. METHODS: We conducted a cross‐sectional study of 211 989 Chi...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546267/ https://www.ncbi.nlm.nih.gov/pubmed/35483962 http://dx.doi.org/10.1111/iju.14915 |
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author | Hu, Xuhuai Yang, Xueying Zhao, Jun Guan, Ting Dai, Qiaoyun Yang, Juan Zhang, Hongguang Zhang, Dongmei Zhang, Yue Shang, Li Ma, Xu |
author_facet | Hu, Xuhuai Yang, Xueying Zhao, Jun Guan, Ting Dai, Qiaoyun Yang, Juan Zhang, Hongguang Zhang, Dongmei Zhang, Yue Shang, Li Ma, Xu |
author_sort | Hu, Xuhuai |
collection | PubMed |
description | OBJECTIVES: To explore the relationship between body mass index and varicocele, the range of body mass index that leads to increased odds of varicocele, and the association between body mass index with the position and grade of varicocele. METHODS: We conducted a cross‐sectional study of 211 989 Chinese males aged 18–65 years participated in the National Free Pre‐conception Check‐up Projects from January 2013 to December 2018. Univariate and multivariate logistic regression models were constructed to assess the association between body mass index and varicocele. RESULTS: Overweight and obese males had 13.1% (odds ratio 0.869, 95% confidence interval 0.838–0.902) and 32.3% (odds ratio 0.677, 95% confidence interval 0.632–0.725) lower odds of varicocele than those with normal body mass index, respectively. The association between them was non‐linear, and males with body mass index of 17.74 to 23.09 kg/m(2) had an increased odds of varicocele. The overweight and obese males had lower odds of left and bilateral varicocele, but the right varicocele odds was increased by 63.3% in obese males. CONCLUSION: Body mass index was associated with the odds of varicocele among reproductive‐age males, but the odds varied by position. The effects of weight management and varicocele on fertility should be taken into account in fertility guidance. |
format | Online Article Text |
id | pubmed-9546267 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-95462672022-10-14 Association between body mass index and varicocele among 211 989 Chinese reproductive‐age males Hu, Xuhuai Yang, Xueying Zhao, Jun Guan, Ting Dai, Qiaoyun Yang, Juan Zhang, Hongguang Zhang, Dongmei Zhang, Yue Shang, Li Ma, Xu Int J Urol Original Articles: Clinical Investigation OBJECTIVES: To explore the relationship between body mass index and varicocele, the range of body mass index that leads to increased odds of varicocele, and the association between body mass index with the position and grade of varicocele. METHODS: We conducted a cross‐sectional study of 211 989 Chinese males aged 18–65 years participated in the National Free Pre‐conception Check‐up Projects from January 2013 to December 2018. Univariate and multivariate logistic regression models were constructed to assess the association between body mass index and varicocele. RESULTS: Overweight and obese males had 13.1% (odds ratio 0.869, 95% confidence interval 0.838–0.902) and 32.3% (odds ratio 0.677, 95% confidence interval 0.632–0.725) lower odds of varicocele than those with normal body mass index, respectively. The association between them was non‐linear, and males with body mass index of 17.74 to 23.09 kg/m(2) had an increased odds of varicocele. The overweight and obese males had lower odds of left and bilateral varicocele, but the right varicocele odds was increased by 63.3% in obese males. CONCLUSION: Body mass index was associated with the odds of varicocele among reproductive‐age males, but the odds varied by position. The effects of weight management and varicocele on fertility should be taken into account in fertility guidance. John Wiley and Sons Inc. 2022-04-28 2022-08 /pmc/articles/PMC9546267/ /pubmed/35483962 http://dx.doi.org/10.1111/iju.14915 Text en © 2022 The Authors. International Journal of Urology published by John Wiley & Sons Australia, Ltd on behalf of The Japanese Urological Association. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Original Articles: Clinical Investigation Hu, Xuhuai Yang, Xueying Zhao, Jun Guan, Ting Dai, Qiaoyun Yang, Juan Zhang, Hongguang Zhang, Dongmei Zhang, Yue Shang, Li Ma, Xu Association between body mass index and varicocele among 211 989 Chinese reproductive‐age males |
title | Association between body mass index and varicocele among 211 989 Chinese reproductive‐age males |
title_full | Association between body mass index and varicocele among 211 989 Chinese reproductive‐age males |
title_fullStr | Association between body mass index and varicocele among 211 989 Chinese reproductive‐age males |
title_full_unstemmed | Association between body mass index and varicocele among 211 989 Chinese reproductive‐age males |
title_short | Association between body mass index and varicocele among 211 989 Chinese reproductive‐age males |
title_sort | association between body mass index and varicocele among 211 989 chinese reproductive‐age males |
topic | Original Articles: Clinical Investigation |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546267/ https://www.ncbi.nlm.nih.gov/pubmed/35483962 http://dx.doi.org/10.1111/iju.14915 |
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