Cargando…
MicroRNA inhibition using antimiRs in acute human brain tissue sections
Antisense inhibition of microRNAs is an emerging preclinical approach to pharmacoresistant epilepsy. A leading candidate is an "antimiR" targeting microRNA‐134 (ant‐134), but testing to date has used rodent models. Here, we develop an antimiR testing platform in human brain tissue sections...
Autores principales: | Morris, Gareth, Langa, Elena, Fearon, Conor, Conboy, Karen, Lau E‐How, Kelvin, Sanz‐Rodriguez, Amaya, O'Brien, Donncha F., Sweeney, Kieron, Lacey, Austin, Delanty, Norman, Beausang, Alan, Brett, Francesca M., Cryan, Jane B., Cunningham, Mark O., Henshall, David C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546319/ https://www.ncbi.nlm.nih.gov/pubmed/35656590 http://dx.doi.org/10.1111/epi.17317 |
Ejemplares similares
-
Polymer Nanoparticles Mediated Codelivery of AntimiR-10b and AntimiR-21 for Achieving Triple Negative Breast Cancer Therapy
por: Devulapally, Rammohan, et al.
Publicado: (2015) -
AntimiR targeting of microRNA-134 reduces seizures in a mouse model of Angelman syndrome
por: Campbell, Aoife, et al.
Publicado: (2022) -
Inhibition of microRNA function by antimiR oligonucleotides
por: Stenvang, Jan, et al.
Publicado: (2012) -
Nanoparticle-complexed antimiRs for inhibiting tumor growth and metastasis in prostate carcinoma and melanoma
por: Kunz, Manfred, et al.
Publicado: (2020) -
Transmission of microRNA antimiRs to mouse offspring via the maternal–placental–fetal unit
por: Hönig, Jonas, et al.
Publicado: (2018)