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MicroRNA inhibition using antimiRs in acute human brain tissue sections

Antisense inhibition of microRNAs is an emerging preclinical approach to pharmacoresistant epilepsy. A leading candidate is an "antimiR" targeting microRNA‐134 (ant‐134), but testing to date has used rodent models. Here, we develop an antimiR testing platform in human brain tissue sections...

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Detalles Bibliográficos
Autores principales: Morris, Gareth, Langa, Elena, Fearon, Conor, Conboy, Karen, Lau E‐How, Kelvin, Sanz‐Rodriguez, Amaya, O'Brien, Donncha F., Sweeney, Kieron, Lacey, Austin, Delanty, Norman, Beausang, Alan, Brett, Francesca M., Cryan, Jane B., Cunningham, Mark O., Henshall, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546319/
https://www.ncbi.nlm.nih.gov/pubmed/35656590
http://dx.doi.org/10.1111/epi.17317

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