Comprehensive phenotyping of human peripheral blood B lymphocytes in healthy conditions

The B cell compartment provides innate and adaptive immune defenses against pathogens. Different B cell subsets, reflecting the maturation stages of B cells, have noninterchangeable functions and roles in innate and adaptive immune responses. In this review, we provide an overview of the B cell subs...

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Autores principales: Carsetti, Rita, Terreri, Sara, Conti, Maria Giulia, Fernandez Salinas, Ane, Corrente, Francesco, Capponi, Claudia, Albano, Christian, Piano Mortari, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Phenotype Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546334/
https://www.ncbi.nlm.nih.gov/pubmed/34664397
http://dx.doi.org/10.1002/cyto.a.24507
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author Carsetti, Rita
Terreri, Sara
Conti, Maria Giulia
Fernandez Salinas, Ane
Corrente, Francesco
Capponi, Claudia
Albano, Christian
Piano Mortari, Eva
author_facet Carsetti, Rita
Terreri, Sara
Conti, Maria Giulia
Fernandez Salinas, Ane
Corrente, Francesco
Capponi, Claudia
Albano, Christian
Piano Mortari, Eva
author_sort Carsetti, Rita
collection PubMed
description The B cell compartment provides innate and adaptive immune defenses against pathogens. Different B cell subsets, reflecting the maturation stages of B cells, have noninterchangeable functions and roles in innate and adaptive immune responses. In this review, we provide an overview of the B cell subsets present in peripheral blood of healthy individuals. A specific gating strategy is also described to clearly and univocally identify B cell subsets based on the their phenotypic traits by flow cytometric analysis.
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spelling pubmed-95463342022-10-14 Comprehensive phenotyping of human peripheral blood B lymphocytes in healthy conditions Carsetti, Rita Terreri, Sara Conti, Maria Giulia Fernandez Salinas, Ane Corrente, Francesco Capponi, Claudia Albano, Christian Piano Mortari, Eva Cytometry A Phenotype Reports The B cell compartment provides innate and adaptive immune defenses against pathogens. Different B cell subsets, reflecting the maturation stages of B cells, have noninterchangeable functions and roles in innate and adaptive immune responses. In this review, we provide an overview of the B cell subsets present in peripheral blood of healthy individuals. A specific gating strategy is also described to clearly and univocally identify B cell subsets based on the their phenotypic traits by flow cytometric analysis. John Wiley & Sons, Inc. 2021-10-18 2022-02 /pmc/articles/PMC9546334/ /pubmed/34664397 http://dx.doi.org/10.1002/cyto.a.24507 Text en © 2021 The Authors. Cytometry Part A published by Wiley Periodicals LLC. on behalf of International Society for Advancement of Cytometry. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Phenotype Reports
Carsetti, Rita
Terreri, Sara
Conti, Maria Giulia
Fernandez Salinas, Ane
Corrente, Francesco
Capponi, Claudia
Albano, Christian
Piano Mortari, Eva
Comprehensive phenotyping of human peripheral blood B lymphocytes in healthy conditions
title Comprehensive phenotyping of human peripheral blood B lymphocytes in healthy conditions
title_full Comprehensive phenotyping of human peripheral blood B lymphocytes in healthy conditions
title_fullStr Comprehensive phenotyping of human peripheral blood B lymphocytes in healthy conditions
title_full_unstemmed Comprehensive phenotyping of human peripheral blood B lymphocytes in healthy conditions
title_short Comprehensive phenotyping of human peripheral blood B lymphocytes in healthy conditions
title_sort comprehensive phenotyping of human peripheral blood b lymphocytes in healthy conditions
topic Phenotype Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546334/
https://www.ncbi.nlm.nih.gov/pubmed/34664397
http://dx.doi.org/10.1002/cyto.a.24507
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