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Mechanisms of action of the sodium‐glucose cotransporter‐2 (SGLT2) inhibitor canagliflozin on tubular inflammation and damage: A post hoc mediation analysis of the CANVAS trial

AIMS: To test the hypothesis that the reduction in urinary kidney injury molecule‐1 (KIM‐1) observed with the sodium‐glucose cotransporter‐2 (SGLT2) inhibitor canagliflozin is mediated through its effects on urine albumin to creatinine ratio (UACR) and monocyte chemoattractant protein‐1 (MCP‐1) by a...

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Detalles Bibliográficos
Autores principales:	Sen, Taha, Koshino, Akihiko, Neal, Bruce, Bijlsma, Maarten J., Arnott, Clare, Li, Jingwei, Hansen, Michael K., Ix, Joachim H., Heerspink, Hiddo J. L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546391/ https://www.ncbi.nlm.nih.gov/pubmed/35635326 http://dx.doi.org/10.1111/dom.14779

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